Nycomed - Global Contract Manufacturing of Pharmaceuticals

Nycomed is a privately owned global pharmaceutical company with a differentiated portfolio focused on branded medicines in gastroenterology, respiratory and inflammatory diseases, pain, osteoporosis and tissue management. An extensive range of OTC products completes the portfolio. Its R&D is built to be open for partnerships beyond its core areas in inflammatory, respiratory diseases and pain as in-licensing is a cornerstone in the company's growth strategy.

The company employs 12,000 associates worldwide, and its products are available in more than 100 countries. It has strong platforms in Europe and in fast-growing markets such as Russia/CIS, and Latin America. While the US and Japan are commercialised through best-in-class partners, Nycomed will further strengthen its position in key Asian markets.

Headquartered in Zurich/Switzerland, in 2008 the company generated total sales of €3.4bn and an adjusted EBITDA of €1.2bn.

Pharmaceutical manufacture, production and packaging

For Nycomed, full service in contract manufacturing extends beyond production and packaging. It means supporting the clients throughout the entire process, assisting in development and scale-up, and providing support in regulatory documentation meeting global standards.

Reliability, responsiveness and a strong focus on results: these virtues form the base for Nycomed’s policy of becoming the preferred pharmaceutical company. Nycomed has established itself among the world’s 25 largest pharmaceutical companies and is the 15th largest provider of over-the-counter medicines. Nycomed Contract Manufacturing Services make the company’s skills, operational excellence and its world-class network available to third-party customers, based on a policy of strong partnership and customer orientation.

Nycomed Contract Manufacturing Services offers the highest level of customer focus in terms of reliable communications – clients are linked directly to the operational managers at the manufacturing sites that have been dedicated to their business. However, it is the tailor-made approach to each and every task of a committed team of experts that makes Nycomed really stand out. It has always been Nycomed’s policy that patients deserve nothing but the best in terms of reliability, quality and responsiveness. With its contract manufacturing services, Nycomed is willing to share this approach with its customers in a strong and economically sound partnership.

Solids, semisolids, liquids and steriles production

Nycomed offers both basic and specialized technologies for bulk production and packaging. With its comprehensive technology portfolio, providing specific and niche technologies, the production capabilities range from nutritional and vitamin products to high potent drugs and other pharmaceutical products. Nycomed also offers a broad range of steriles based on a variety of ingredients, including biologics.

Our technology portfolio for the bulk production of solids includes:

• Mixing and granulation (wet, fluid bed and roller compaction)
• Pellet production (non pairelles, extrusion, Wurster coating)
• Tabletting (cores for various tablet types, e.g. bi-layer tablets)
• Encapsulation
• Coating (aqueous and organic)
• Imprinting

Our service for packaging of solids includes blister in various formats (PVC, PVC/PVDC, Alu/Alu, Aclar), bottles (glass, PE), wallet packaging and stick packs.

Our technology portfolio for the production of liquids and semisolids comprises liquids, liquid preparations and semisolids.

Liquids:

• Bottles
• Sachets
• Ampoules
• Vials
• Cartridges and syringes

Liquid preparations:

• Blow fill seal (gels, liquids)
• Nasal sprays

Semisolids:

• Stick packs
• Ointments
• Suppositories
• Foil packs

Nycomed's technology for the production of steriles encompasses lyophilization and aseptic spray drying.