Drug Delivery Systems

ADD Technologies
Pellets manufactured with CPS™ technology (left) and with conventional extrusion / speronization technology (right).	MicroPx™ technology – micro pellet delivery system.	Ibuprofen DC 100 manufactured with ProCell™ technology – the mean particle size is 300µm, and it has high density and low porosity.
Tablets manufactured with Ibuprofen DC100 (left), and with conventional Ibuprofen (right).	In-vitro dissolution profiles of products with different onset times.

Aveva
Crystal reservoir technology has resulted in smaller patches with a more controlled and sustained drug release.	A sustained release is facilitated through the consistent rejuvenation of drug molecules at the surface of the skin.	A burst release is consistent with a rapid release of drug at the surface of the skin.
A chrono-controlled release reflects the circadian rhythm of the patient.	Cadaver skin permeation testing helps determine the feasibility of a compound to be incorporated into a transdermal drug delivery system.

Baxter Healthcare Corporation's BioPharma Solutions Business
For more than 20 years, Baxter Healthcare Corporation’s BioPharma Solutions business has partnered with pharmaceutical companies to enhance their parenteral product offerings.	Baxter’s liquid and frozen premix systems eliminate many of the complex procedures required for traditional IV admixture and compounding.	SOLOMIX is the only admixture system that integrates the vial, transfer device and diluent container in one point-of-care system.
CLEARSHOT copolymer syringe technology offers a unique manufacturing process that’s ideal for both small and large molecules.

Biodar
Microencapsulation of small (less than 1mm diameter) solid particles enables the absorption of the active material in a similar pattern and rate either in a fasting or in an eating mode.	Alginate beadlets provide encapsulation protection and delivery options for hydrophobic drugs, which may come in oily phase.	Venlafaxine HCL 150mg ER - Biodar vs Effexor ER.
Biodar has launched a new user-friendly website and changed its company logo. As an emerging company with an innovative line of beadlets, minerals, vitamins and amino acids, shaping the company's image is one of Biodar top priorities.	Biodar develops both generic and Added Value Generic dosage forms as joint ventures according to the customers' specific requirements. Biodar's portfolio of development candidates is mainly USA oriented.

Capsulution
Encapsulation technology, which provides high-end capsules.	Capsules can be produced in any size (from 500 nanometres up to 50 microns) and be fitted with almost any biochemical, electrical, optical and magnetic features.	Functionally designed and custom-made, these capsules suit a variety of pharmaceutical and non-pharmaceutical purposes.
Multifunctional nano- and micron-sized capsules which are invisible to the human eye.	Development of products ranging from the non-invasive blood sugar measurement to the stabilization and protection of drug substances.

Crossject
Crossject's needle-free injection device eliminates the risk of needle-stick and needle contamination.	The injection process is simple and reliable.	The pharmaceutical sub-assembly includes glass tube, pistons and nozzle made of standard materials and can be easily be filled in on conventional filling lines.

Eurand
Eurand's microencapsulated drugs can be taste-masked and directly compressed with Advatab to ensure an optimised drug delivery process.	Coacervation microencapsulation of Acetaminophen.	Diffucaps drug delivery technology enables unique pk profiles and flexible dosing.
Multiparticulate customized release technology provides a flexible approach to drug release requirements.	Biorise drug delivery technology enhances the solubility and bioavailability of activated drug substances.

Ing Erich Pfeiffer
We are one of the world’s leading manufacturers of pharmaceutical sprays.	The cartridge spray system ensures a smooth reliable performance every time.	The upside down pump is consistently excellent.

INyX Pharma
INyX Pharma specializes in niche products and technologies for the treatment of respiratory, allergy, dermatological and topical conditions.	Key acquisition targets include high-quality manufacturing operations that offer complementary services to our current sterile fill and drug delivery capabilities.	INyX is one of only three independent pharmaceutical companies to have FDA, Canadian and European regulatory approvals for pharmaceutical aerosol production.
INyX will leverage aerosol drug delivery technology to develop proprietary products.

JRS Pharma
PROSOLV® SMCC (Silicified Microcrystalline Cellulose) is the high functionality excipient of choice for the pharmaceutical industry.	JRS manufactures the largest portfolio of branded excipients.	JRS Pharma manufactures and markets EXPLOTAB, the first superdisintegrant, to ensure consistent quality, availability and the premier technical support for which we are known.
PRUV, Sodium Stearyl Fumarate, offers excellent dissolution rates, is not sensitive to overblending and enhances lubrication efficiency.	PROSOLV is a high functionality technology platform, enhancing the characteristics of APIs and other ingredients.

LTS
LTS supports all transdermal therapeutic patch system variations, focusing on the requirements of the individual patient.	LTS' oral wafer medication systems use the mouth as a site of both application and drug action.	The flat dosage form of LTS' oral wafer medication systems can vary between 2cm² and 8cm² in area, and 20µm and 500µm in thickness.
LTS supplies flash release, mucoadhesive melt-away and mucoadhesive sustained release oral medicinal wafers.	Estradiol can be delivered most efficiently by HRT patches that use LTS' transdermal method.

Micro-Sphere
Micro-Sphere's factory in Madonna del Piano is very close to Lugano airport, between Milano and Zürich airports.	SEM picture of Lacto-Sphere® MM3 micronized.	SEM picture of Lacto-Sphere® MM250 sieved.
Particle size distribution profile of Lacto-Sphere® MM3.

Mylan
Mylan manufactures a wide range of transdermal products that includes branded films, transdermal backings and medical laminates.	Mylan gained FDA approval in 2000 to manufacture and sell a generic seven-day estradiol patch.	We supply an extensive list of branded films, transdermal backings and medical laminates.

NXP Semiconductors
Track your respective drugs with our chip solutions.	Consumers are protected from non-genuine drugs.	RFID has been recognized as one of the most promising technologies to secure the pharmaceutical supply chain.
The RFID tag is unique and has a one-time-programmable user memory that locks the user data after programming.

Owen Mumford
Single dose and multi dose reusable and disposable autoinjectors and injection pen (e.g. insulin pens) systems.	Owen Mumford auto injectors feature needle shield removal, automatic needle insertion and automatic injection to a pre-determined depth.	Parenteral drug delivery systems for controlled, consistent injections.
Owen Mumford auto injectors are compatible with a wide range of pre-filled glass and plastic syringes, and pre-filled cartridges.	Automatic injection devices simplify self-injection, overcome user dexterity issues and reduce needle phobia.

Presspart Manufacturing
Presspart has a reputation for quality aerosol cans.	We have in-house coating capability.	We are the only commercial supplier of stainless steel MDI cans in the world.
All of our operations are CGMP compliant.

Santapet Polymers
'Injection-Blow Moulding' in relative terms is the fusion of two processes, i.e. the injection process and the blow process.	To provide an efficient leak proof pack, we have given a groove in the nozzle, and a corresponding collar on the neck of the bottle.	To provide a seal of tampering, the dropper bottle has been designed in such a way that once the cap fits over the thread and the ratchet smoothly.

Scandinavian Health Ltd (SHL)
SHL provides a broad range of capabilities including high precision molding, design and metrology.	Auto-injectors enable patients to self-administer medications.	SHL produces a wide range of high-quality products for major pharmaceutical and biotech companies.
The DAIM is a single-use disposable auto-injector that is used to administer a variety of medications to treat diseases such as multiple sclerosis.	SHL's expert engineers design and develop state-of-the-art automation equipment in-house.

Sigmoid Biotechnologies
Sigmoid Biotechnologies is a speciality pharmaceutical company engaged in the development of pharmaceutical products based on its novel oral drug delivery technologies.	From drug delivery to product enhancement, Sigmoid is your answer to poor or insoluble compounds.	Sigmoid is an innovative speciality pharmaceutical company that meets the challenges of the pharmaceutical and biotechnology industries using its proprietary technologies.

Systopic Laboratories
Systopic is the pioneer in the production of Rextop-1% gel for psoriasis.	Systopic develops USFDA approved innovative formulation for acne vulgaris.	AF-400 is a high strength effective anti-fungal agent used to treat infections caused by Candida albicans and cryptococcus neoformans.
Topisal is the topical steroid + keratolytic agent product that reduces the thickness of stratum corneum and increases shedding of corneocytes in normal skin.	AMACE-BP is highly effective for managing cardiac ischemia and hypertension.

Unigene
Unigene's cGMP manufacturing facility is equipped with all necessary technology for the implementation of bacterial and mammalian fermentation, high-tech purification methodologies and analytical testing processes.	Our recombinant 'direct expression' technology is central to the scalable and effective production of peptides and small proteins.	A Unigene large fermenter unit.
Our main drug product lines include nasal / oral salmon calcitonin - oral PTH analogs, oral glucose and regulatory peptides.	cGMP gel loading process in operation.

Ypsomed
Ypsomed company headquarters in Burgdorf, Switzerland.	Reusable pen injectors for reliable and accurate dosing of insulin, hGH and other frequently injected drugs.	Patented disposable 'dose memory' pens and 'click-on' pen needles make giving injections more convenient.
Disposable and reusable auto-injector platforms provide safe and easy injections from pre-filled syringes.	High level of technological integration for the development and manufacture of pens, pen needles and auto-injectors.

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