Roquette is a long-established supplier of raw materials, excipients and actives to the pharmaceutical and cosmetic industries, which also benefit from its valuable services.
Oral dosage forms are still the most commonly-used formulations, generating a complex list of manufacturing, regulatory and consumer-related issues. Among Roquette's trusted excipients and services there are some particularly suitable solutions for dilution, direct compression, filling, disintegration, encapsulation and / or film-forming coating.
Mannitol has some of the most desirable of excipient profile qualities, making it one of the most suitable diluents for moisture-sensitive formulation, coupled with a pleasant taste and mouthfeel. Roquette has been working continuously on improving these remarkable intrinsic properties, thereby creating an exceptional mannitol PEARLITOL® range: PEARLITOL® C, PEARLITOL® SD, PEARLITOL® DC, PEARLITOL® FLASH and PEARLITOL® PF.
Mannitol PEARLITOL® SD and DC are widely used and particularly adapted to direct compression. High-quality chewable, orodispersible or suckable tablets, with a pleasant taste and texture, can also be formulated and produced very easily with new directly compressible polyols such as PEARLITOL® Flash (a new mannitol compound), SweetPearl® P 300 DC (DC maltitol), XYLISORB® DC (DC xylitol) and NEOSORB® P 150 DC and P 300 DC (DC sorbitol).
Other excipients are also part of Roquette Pharma direct compression solutions:
To help you in your scaling-up process, Roquette also provides a new compression simulation service through a public / private partnership with an academic institution.
Roquette's pioneering GLYCOLYS® sodium carboxymethyl starch has for decades set the reference standard for the super-disintegration function in solid dosage forms. The company has developed different grades offering, for instance, particular viscosity, pH or solvent-free properties.
The unique composition of KLEPTOSE® LINECAPS (a short-chain amylose ingredient) is ideal for taste masking and encapsulation of apolar molecules in many dosage forms (liquids, chewable tablets, ODT, suspension, etc.). It is particularly suited to the paediatric and nutraceuticals markets.
LYCOAT® film coating polymer and ReadiLYCOAT® ready-to-use coating systems allow tablets to be coated very quickly and to a high standard. Moreover, LYCOAT® film coating polymer delivers exceptional inertness where other coating polymers fail. Roquette offers on-site assistance for your trials, process parameters optimisation, etc.
Oral dosage forms play an important role in primary care, in particular for paediatric formulations.
LYCASIN® is a maltitol syrup with properties ideal for the preparation of sugar-free syrups, lozenges and jellies, being widely used for confectionery applications. In the pharmaceutical industry, LYCASIN® is also a sucrose replacement in preparations suitable for diabetics.
Parenteral preparations are essential life-saving drugs requiring reliable pyrogen-free ingredients.
Thanks to the intimate knowledge of its customer's needs, Roquette is a trusted leader in the parenteral preparations market. It offers a reliable, pyrogen-free range of products, including pyrogen-free dextrose monohydrate LYCADEX® PF (for which it has launched a brand new dedicated production plant); mannitol PEARLITOL® PF; sorbitol NEOSORB® PF; and parenteral-grade hydroxypropyl betacyclodextrin KLEPTOSE® HPB/HP.
Check our website to discover the other products and services also available from Roquette Pharma.
Pharmaceutical & Cosmetics Business Unit
62080 LESTREM Cedex
Tel: +33 3 21 63 36 00
Fax: +33 3 21 63 94 64
URL: PEARLITOL® FLASH self-disintegrating filler
URL: ReadiLYCOAT™ film forming and coating polymer
URL: LYCADEX® PF pyrogen-free dextrose monohydrate