Olink Bioscience - Reagent Kits for Highly Sensitive Protein Detection

Olink Bioscience is commercializing cutting-edge technologies for analysis of proteins and nucleic acids. These novel tools enable researchers to see further into biology revealing new insights into basic science, drug development, and diagnostics. The company's proprietary product lines include: Duolink, a reagent kit for visualization and quantification of individual proteins, their interactions and modifications, in unmodified cells and tissues; and Proseek, an open assay development reagent kit for analyzing proteins in only 1µl of serum or plasma samples with high sensitivity.

Olink's molecular technologies are also commercialized through partnerships with industry-leading organizations such as Affymetrix and Life Technologies.

Reagent kits for detection and localization of protein interactions in situ

The Duolink kit offers a fast, reliable and higher throughput alternative to co-IP assays. For the first time, any protein target can be readily detected and localized at the same time with single molecule resolution. Utilizing only a few cells, sub-cellular events, even transient or weak interactions, are revealed in situ and sub-populations of cells can be differentiated.

Proteins, their interactions and modifications, can also be objectively and accurately quantified in unmodified cells and tissues. Each Duolink kit consists of customizable kit components and can be configured to meet specific assay requirements. In addition to the kit components you will also need two primary antibodies raised in different species.

Reagent kits for protein quantification in small sample volumes

Does your protein assay consume too much of your precious sample? Is long assay development time slowing down your research?

Proseek is intended to be used for detection and quantification of a single protein in suspension, e.g. plasma and serum. It offers the same level of simplicity and openness as an ELISA but requires only 1µl sample volume, which enables you to make better use of your precious samples, e.g. from limited biobanked material and small animal models. It also delivers excellent assay performance from a simple working procedure.

The simple technology concept ensures specificity, sensitivity and reliability. It also offers the benefits of detection using real-time PCR, allowing quantification of both relative and absolute protein levels. With very little optimization required new assays can be developed for any target protein within a day. The Proseek kit consists of three components that can be ordered separately.

Plasma biomarker discovery service

Make the most of your precious samples, with maximized information from minimized sample amount. Olink Bioscience offers the opportunity to have your precious biobanked plasma samples analyzed for up to 74 potential cancer biomarkers in no more than 2µl of sample. The 74 protein assays are available in four panels, where each assay has been accurately validated for sensitivity, recovery, dynamic range, specificity and precision.

Biomarker studies that previously have been limited by poor assay sensitivity, low throughput systems and insufficient sample amount are now feasible in a simple and efficient way through Olink's plasma biomarker discovery service.