Norgen Biotek Sample Preparation and Preservation Kits for Nucleic Acid and Protein Purification, Concentration and Clean-Up
Norgen Biotek is an innovative biotechnology company that develops and manufactures patented sample preparation and preservation kits for nucleic acid (DNA and RNA, microRNA) and protein purification, concentration and clean-up. Norgen Biotek offers comprehensive products and services in the following areas:
- RNA and microRNA purification, concentration and clean-up kits
- DNA purification and clean-up kits
- Protein purification, concentration and clean-up kits
- Urine DNA / RNA / protein preservation, concentration and isolation (kits and reagents)
- Saliva DNA preservation, concentration and isolation (kits and reagents)
- Blood / plasma / serum RNA, miRNA, DNA sample preparation
- Molecular diagnostics kits (isolation, amplification and detection) for research purposes only for human pathogens, food-borne pathogens, plant pathogens and animal pathogens
- PCR reagents
- DNA and RNA molecular weight ladders
- Chemicals and buffers
- Plastics and filtration spin columns
- Liquid filling in clean room environment
- Kit development and manufacturing (under ISO13845 standards)
Norgen operates in a state-of-the art facility complete with clean room environment, and the company is ISO9001 and ISO13845 certified and GMP compliant. Norgen has two products registered with the FDA: urine DNA, RNA and protein concentration and preservation; and saliva DNA collection and preservation.
Urine collection, concentration, preservation and isolation
Norgen has developed unique urine concentration and preservation devices which allow for the concentration of urine analytes simply and rapidly. The urine preservative provided with these devices allows for the urine DNA, RNA and proteins to be preserved at ambient temperatures, which simplifies the transportation of specimens from the clinic or field (resource-limited areas) to the lab, as there is no requirement for refrigeration or freezing.
The urine DNA, RNA and proteins in preserved samples are stable for a year at room temperature. The provided urine preservative also prevents the growth of bacteria and fungi and inactivates viruses, thus collected urine specimens can be safely shipped concentrated (50X) at ambient temperature. Norgen’s urine concentration and preservation devices are available bundled with the reagents for purification of high-quality DNA, RNA or proteins from the preserved samples.
Urine concentration and preservation device
A unique feature of this urine concentration and preservation device is that it also allows for the isolation of DNA, RNA, miRNA and proteins without the use of centrifugation and therefore can be used in the field in a resource-limited setting.
We have also made our urine preservative available to researchers in both liquid format and dried format in various sized tubes to allow the collection of urine in any amount suitable for any assay. Therefore, Norgen is a one-stop shop for all urine preservation and transport needs.
Saliva DNA collection, preservation and isolation
Norgen has also developed a saliva DNA collection, preservation and isolation kit that is an all-in-one solution designed for simple and non-invasive saliva collection; preservation of DNA in saliva samples at ambient temperature; and isolation of high-quality DNA within a laboratory setting for use in downstream diagnostic assays.
Saliva DNA collection and preservation kits
The kit contains individualized saliva DNA collection and preservation kits which consist of a saliva collection tube and Norgen’s saliva DNA preservative contained within a sealed, squeezable ampoule. Saliva samples are collected and the saliva DNA preservative is then added.
Norgen’s saliva DNA preservative is an aqueous storage buffer designed for rapid cellular lysis and subsequent preservation of DNA from fresh specimens. The buffer prevents the growth of bacteria and fungi, and also inactivates viruses, allowing the resulting non-infectious samples to be handled and shipped safely. In addition, the buffer eliminates the need to immediately process or freeze samples and allows the samples to be shipped to centralized testing facilities at ambient temperature. The components of the buffer allow samples to be stored for more than two years without any detectable DNA degradation.
Additional sample collection and preservation kits
Norgen also has additional sample collection and preservation products including the buccal DNA collection and preservation kit, blood DNA preservation buffer, sample collection kit for upper respiratory tract infectious agents, and swab collection and preservation kit for urogenital / rectal samples. All these products allow for preservation of DNA / RNA / proteins at ambient temperatures, and all are compatible with Norgen’s purification kits.