Anu's Laboratories - Basic and Advanced Quality Drug Intermediates and Active Pharmaceutical Ingredients

Anu’s Laboratories is one of the leading manufacturers and suppliers of basic and advanced quality drug intermediates and Active Pharmaceutical Ingredients (API) in India. Strong capabilities in process chemistry coupled with a highly qualified team of scientists, allow us to offer a wide range of complex organic molecules and to extend support to synthesis of new chemical entities.

BASIC AND ADVANCED DRUG INTERMEDIATES

Anu’s Laboratories is the exclusive manufacturer and exporter of basic and advanced drug intermediates such as 2,4 dichloro 5-fluoroacetophenone, cis (+) hydroxy lactam, chlorohexan-2-one, sodium methoxide solution and powder, fluoro chloro quinolonic acid (ciprofloxacin and norfloxacin), 2-amino pyrazine, 3’-chloropropiophenone, propiophenone and 5 amino-2, 4, and 6-triodo-isophthaloyl dichloride (ATIPA dichloride) (IOPAMIDOL).

Anu’s Laboratories also manufactures APIs such as pentoxifylline BP / USP and diltiazem hydrochloride.

2,4-DICHLORO-5-FLUOROACETOPHENONE

2,4-dichloro-5-fluoroacetophenone is the basic starting intermediate used in the manufacture of ciprofloxacin hydrochloride, an antibacterial used all over the world. The current production volume of this intermediate is about 100t per month.

CIS (+) HYDROXY LACTAM (DILTIAZEM HYDROCHLORIDE)

Cis (+) hydroxy lactam is an advanced chiral intermediate used in the manufacture of diltiazem hydrochloride, a calcium ion influx inhibitor (a slow channel blocker or calcium antagonist). The company has optimised the resolution technology for marketing cis (+) hydroxy lactam and has the capacity to produce more than 30t per month.

SODIUM METHOXIDE

Sodium methoxide is an organic salt available in solution as well as powder form. Anu’s Laboratories has become one of the leading manufacturers of sodium methoxide solution and its powder by following the highest quality standards.

Sodium methoxide is widely used as a catalyst and a strong base in synthetic organic chemistry as well as being employed in bio-diesel production. It is also used in medicines, pesticides, intermediates and edible fat.

1-CHLORO-5-HEXANONE

The company offers high-quality 1-chloro-5-hexanone, a vital intermediate in the manufacture of pentoxifylline, which is used to improve blood flow in patients with circulation problems, reducing aching, cramping and tiredness in the hands and feet.

Anu’s Laboratories possesses a very competitive technological edge over pentoxifylline manufacturers who produce chlorohexanone to meet their captive consumption.

QUALITY AND SERVICE

All our basic and advanced quality drug intermediates and active pharmaceutical ingredients are manufactured under the most carefully controlled conditions. Our manufacturing plant operates in compliance with cGMP guidelines. The major activities of quality assurance include:

• Documentation and change control
• Internal Quality Audits (IQA)
• cGMP training
• Validation of process, equipment, equipment cleaning and analytical test methods
• Handling customer complaints
• Monitoring quality trends
• Stability studies and impurity profiles as per ICH guidelines

RESEARCH AND DEVELOPMENT

Anu’s Laboratories boasts of a highly qualified team of scientists. The company has experience with a wide range of chemical reactions including aldol condensations, diazotization, amination, Friedel-Craft reactions, borane reagents, Grignard reactions, bromination, halogen exchange, butylithium, high pressure reactions, chloroacylation, high vacuum fractional distillations, Cannizzaro reactions, hydrohalogenations, cryogenic reactions, Lewis' acid mediated ring closures, cynation, Michael addition, Darzen reaction, optical resolution and DCC / CDI couplings.

CONTRACT PROCESS RESEARCH AND CUSTOM MANUFACTURING

Anu’s Laboratories is involved in contract process research and custom manufacturing. The company possesses a fully equipped multi-purpose unit capable of processing and developing technologies for advanced intermediates for API's and NCEs. The company also provides technology transfer and scale-up services on a contract, FTE or project by project basis, depending on the requirements of the customer.

ACHEIVEMENTS AND AWARDS

Established in 1996, Anu's Laboratories is an ISO 9001 certified company. The company has won major industry awards that include:

• 'State Level First Best Entrepreneur (SSI) award for the year 2001-2002' by Government of Andhra Pradesh, Commissioner of Industries, India
• ISO 9001 and Q9001-2000 certification
• Anu's R&D department is recognized by the Department of Scientific and Industrial Research (DSIR), Govt. of India, New Delhi