MIP Technologies and Supelco Launch a New SPE Application for the Selective Extraction of Chloramphenicol from Shrimp
06 June 2008
The SupelMIP™ SPE-Chloramphenicol, a new application for extraction of chloramphenicol from shrimp, improves selectivity, decreases the amount of interfering compounds, reduces analysis time and improves detection limits (low ppt range) compared with existing SPE phases on the market.
MIP Technologies AB and Supelco, a division of the Sigma-Aldrich® Group (NASDAQ: SIAL), announced today the launch of a new SupelMIP application for the selective extraction of chloramphenicol from shrimp using SupelMIP SPE-chloramphenicol cartridges.
Chloramphenicol (CAP) is a broad spectrum antibiotic that has been determined as a probable causative agent of aplastic anaemia and is a possible carcinogen in humans. Because of these health concerns, the EU, the US and Canada have banned the use of CAP in aqua-culture, food-producing animals and livestock.
Today, a zero tolerance level for food is in place since maximum tolerance levels cannot be established for compounds with this level of toxicity.
A simple, fast, selective and highly sensitive solid phase extraction (SPE) application has been developed for trace level determination of CAP in shrimp.
Recoveries are above 90%, the extracts show minimized ion suppression and the detection limits are in the low ppt (part per trillion) range.
“This new SupelMIP application in combination with mass spectrometry (MS) detection leads to higher throughput and gives lower detection limits than other methods on the market, benefits that are particularly advantageous where trace level detection and routine analyses are required,” said Dr Christine Widstrand, Chief Business Officer at MIP Technologies.
“The SupelMIP SPE chloramphenicol application for extraction of CAP from shrimp provides improved and significant increases in selectivity relative to conventional hydrophilic polymer SPE. Both attributes are critical for achieving lower limits of detection and quantitation during trace analysis,” said An Trinh, Product Manager, Supelco.
The SPE sorbents based on molecularly imprinted polymers have been developed by MIP Technologies. SupelMIP is a trademark of Supelco, the worldwide product distributor.
