Malvern Instruments

Drug Development Technologies

Characterising Thermotropic Phase Transitions in Lipid Bilayer Membranes Using Differential Scanning Calorimetry

Malvern Instruments

Lipids form a bilayer in or onto the surface of cell membranes, which incorporate or bound proteins and other constituents.

Biological membranes require a mainly fluid environment for proper function, but different states of fluidity are also important, as these provide membrane compartmentalisation (such as lipid-raft domains in plasma membranes, where a liquid-ordered phase is present) related to protein insertion and function.

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