DoverPac Granulator Containment Technology and Tablet Coater Containment System - O'Hara LCM Tablet Coater08 October 2010 by ILC Dover
In the pharmaceutical industry, granulation is used to create bonds between multiple particles as part of the oral solid dosage manufacturing process. Two types of granulation technologies are employed: wet granulation and dry granulation.
The containment systems described in this guide center around wet granulation, which involves the massing of a mix of dry primary powder particles using a granulating fluid. The powders can range in properties and potency and are subjected to a variety of additional steps including sieving, drying and milling.
Used for lab scale and production operations at multiple international pharma manufacturers, our contained granulator applications take the idea of retrofits to another level. Here, a broad range of existing and new equipment are supported as a tool to eliminate the risk of contained powder processing.
Recently delivered for lab scale operations at an international pharma manufacturer, the installation described in this containment guide takes the idea of retrofits to another level. Here, a new piece of equipment was needed but cost savings were realized by modifying an existing design. Flanges added to the unit by the original equipment manufacturer (OEM) allow this end user to process contained when needed and to use existing procedures when containment is not required.
Containment for the O'Hara LCM tablet coater is provided by two individual rectangular enclosures. One enclosure surrounds the pan access door and the second the exhaust plenum access door. The enclosure is manufactured from clear ArmorFlex® film that allows room light to illuminate inside the enclosure for easy viewing.
This rugged film provides a safe working environment while enabling the enhancements developed through numerous installations using this flexible containment technology.
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DoverPac Granulator Containment Technology and Tablet Coater Containment System - O'Hara LCM Tablet Coater