Central Institute for Translational Cancer Research (TranslaTUM), Technical University of Munich, Germany
The Central Institute for Translational Cancer Research (TranslaTUM) is a new interdisciplinary research building officially inaugurated at the Technical University of Munich in September 2017.
The building was developed by Free Federal State of Bavaria with the support of the German Federal Ministry of Education and Research.
Developed at a cost of €60m ($71.64m), the research facility received a €24m ($28.65m) contribution from the federal Government of Germany.
TranslaTUM building design and features
The six-storey, S-shaped TranslaTUM research building has a total floor space of 5,600m². It features an entrance hall with an open and curving staircase.
The facade of the building is arranged horizontally with a number of long, thin windows. It also includes white, grooved ceramic plates, which highlight the wave-shaped structure.
Public areas include a cafeteria, a seminar area, and an auditorium.
Facilities at the TranslaTUM research building
The building features 4,000m² research labs, which can accommodate up to 230 researchers.
Designed to carry out research in translational oncology, the facility is constructed adjacent to the Technical University of Munich's (TUM) hospital Klinikum rechts der Isar to support rapid translation of novel knowledge and technology into patient care. It provides physicists, engineers, and physicians with a shared new laboratory for transdisciplinary research.
The facility's staff will focus on tumour diseases of bone marrow and the digestive tract, exploring the process of recognising and sending molecular signals in tumour cells. They will also study the impact of cancer cells on the immune system with the help of new imaging and analysis methods.
The facility will allow collaboration among different disciplines including biology, biomedicine, biochemistry, physics, engineering sciences, and the doctors in clinics.
The facility includes a 700m² seminar and conference area and an underground garage with 50 parking spaces.
Technology at TranslaTUM research building
The TranslaTUM research building has core facilities including imaging, preclinical research, and cell analysis. It also features state-of-the-art laboratory equipment in core facilities including a central sequencing unit, a microscopy unit, a histology lab, and a central bioinformatics unit.
The facility is equipped to offer a broad variety of imaging studies using established and validated methods such as good manufacturing practice (GMP) produced radiopharmaceuticals. The imaging infrastructure at the facility includes magnetic resonance (MR), multi-spectral optoacoustic tomography (MSOT), ultrasound (US), positron emission tomography (PET), single-photon emission computed tomography (SPECT), computed tomography (CT), and phase contrast-CT technology.
The laboratory at the facility is in compliance with S2-biolevel safety standards. A 700m² area is meant for animal holding, where mice and rats can be retained in sealed rooms.
Animal holding areas comply with animal welfare and hygiene standards, and are equipped with high-efficiency particulate absolute (HEPA) and odour filters to stop the spread of incoming or outgoing particles.
TranslaTUM construction details
Construction of the new research building began in 2014 and the first floor of the building was completed in July 2015. The topping out ceremony was held in November 2015.
Contractors involved with TranslaTUM
doranth post architekten was awarded a contract to provide designs for laboratories, offices, the seminar area, the cafeteria and underground parking in the research building.