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The new Richter facility was designed primarily to produce finished contraceptives and active bulk ingredients for export.
The new Richter facility was designed primarily to produce finished contraceptives and active bulk ingredients for export.
Richter has a wide portfolio of contraceptive products, which includes finished products as well as second- and third-generation tablets.
Richter has a wide portfolio of contraceptive products, which includes finished products as well as second- and third-generation tablets.
 Validation of production to a level that would result in FDA accreditation was a major concern during the realisation of the turnkey project.
Validation of production to a level that would result in FDA accreditation was a major concern during the realisation of the turnkey project.
Richter plans to begin selling its successful emergency contraceptive product in the USA, where it has been registered, in the near future.
Richter plans to begin selling its successful emergency contraceptive product in the USA, where it has been registered, in the near future.
 Map showing Richter Gedeon Vegyeszeti Gyar Rt's new facility in Budapest, Hungary.
Map showing Richter Gedeon Vegyeszeti Gyar Rt's new facility in Budapest, Hungary.
 Location of Searle Pharma's new medication production plant in Izvarino, Moscow.
Location of Searle Pharma's new medication production plant in Izvarino, Moscow.
The CTF showing the atrium meeting area.
The CTF showing the atrium meeting area.
 Topping out in December 2004.
Topping out in December 2004.
 Fit-out was 70% complete by the time construction of the building was completed.
Fit-out was 70% complete by the time construction of the building was completed.
Facilities are state-of-the-art for Biotech SMEs.
Facilities are state-of-the-art for Biotech SMEs.
 The CTF nearing completion.
The CTF nearing completion.
 The CTF from the side elevation.
The CTF from the side elevation.
The architecture of the building is a design of steel and glass.
The architecture of the building is a design of steel and glass.
 The production hall.
The production hall.
 The NovoSeven facility from the outside.
The NovoSeven facility from the outside.
Fermentation vessels in the production area.
Fermentation vessels in the production area.
 A floor plan of the facility.
A floor plan of the facility.
 One of the company's key products is NovoSeven, a clotting agent used for treatment of patients with haemophilia.
One of the company's key products is NovoSeven, a clotting agent used for treatment of patients with haemophilia.
The NovoSeven plant was constructed in a modular fashion – much of the plant was constructed offsite and then fitted together later.
The NovoSeven plant was constructed in a modular fashion – much of the plant was constructed offsite and then fitted together later.
 The main production building before the start of the new expansion.
The main production building before the start of the new expansion.
 Renagel for dialysis patients.
Renagel for dialysis patients.
Process R&D at Genzyme, Waterford.
Process R&D at Genzyme, Waterford.
 Media preparation for biologics manufacture at Waterford.
Media preparation for biologics manufacture at Waterford.
 Some of the dosage forms for Renagel, including two tablet types and a new capsule.
Some of the dosage forms for Renagel, including two tablet types and a new capsule.
Psoriasis drug Amevive (alefacept) may be produced at the Hillerød facility.
Psoriasis drug Amevive (alefacept) may be produced at the Hillerød facility.
 Avonex (Interferon beta-1a), Biogen Idec's best-selling treatment for MS, will be the first drug produced at the Danish plant.
Avonex (Interferon beta-1a), Biogen Idec's best-selling treatment for MS, will be the first drug produced at the Danish plant.
 The plant is in an area known as 'Medicon Valley' because of its attractiveness to pharmaceutical companies.
The plant is in an area known as 'Medicon Valley' because of its attractiveness to pharmaceutical companies.
Biogen Idec has already secured an option to buy an adjacent 36-acre site for the second phase of construction at Hillerød.
Biogen Idec has already secured an option to buy an adjacent 36-acre site for the second phase of construction at Hillerød.
 A section of the process equipment from the new large scale manufacturing plant.
A section of the process equipment from the new large scale manufacturing plant.

The buildings are of steel frame construction with overlaying siding facades.
The buildings are of steel frame construction with overlaying siding facades.
 Rockwool Denmark is providing insulation panels for the construction.
Rockwool Denmark is providing insulation panels for the construction.
 One of the drugs to be produced at the plant is Avonex. This will also be packaged in the new packaging and laboratory complex.
One of the drugs to be produced at the plant is Avonex. This will also be packaged in the new packaging and laboratory complex.
Tysabri is a new Biogen Idec drug to treat psoriasis and this will also be produced at the Hillerød plant for European distribution.
Tysabri is a new Biogen Idec drug to treat psoriasis and this will also be produced at the Hillerød plant for European distribution.
 A remote operator station in the Indena plant.
A remote operator station in the Indena plant.
 The top of a reactor vessel at the Indena pharmaceutical plant.
The top of a reactor vessel at the Indena pharmaceutical plant.
Fisher control valves at the Indena plant. The valves are fitted with FIELDVUE digital valve controllers.
Fisher control valves at the Indena plant. The valves are fitted with FIELDVUE digital valve controllers.
 Yew Tree, from which anti-cancer compound IDN 5390 is derived.
Yew Tree, from which anti-cancer compound IDN 5390 is derived.
 The new plant in Ravensburg South.
The new plant in Ravensburg South.
Part of the vial filling process.
Part of the vial filling process.
 A dual chamber vial.
A dual chamber vial.
 A dual chamber pre-filled syringe, one of Vetter’s specialities.
A dual chamber pre-filled syringe, one of Vetter’s specialities.
A further part of the vial filling and manufacturing process.
A further part of the vial filling and manufacturing process.
 Facilities for production are of the highest quality.
Facilities for production are of the highest quality.
 The plant is fully integrated for production and packaging.
The plant is fully integrated for production and packaging.
The Scada work stations have an easy to use interface.
The Scada work stations have an easy to use interface.
 The production equipment all has the latest CIP and DIP systems.
The production equipment all has the latest CIP and DIP systems.
 The NOTOL plant is a new concept in pharmaceutical manufacture.
The NOTOL plant is a new concept in pharmaceutical manufacture.
The NOTOL plant is a state of the art production facility.
The NOTOL plant is a state of the art production facility.
 The new Roche office building from across the river in Basel will hold 2,400 employees.
The new Roche office building from across the river in Basel will hold 2,400 employees.
 The new biotech building blends into the Basel architecture.
The new biotech building blends into the Basel architecture.
The new biotech building from a different aspect.
The new biotech building from a different aspect.
 The new biotech building makes use of all the natural light it can to be environmentally friendly.
The new biotech building makes use of all the natural light it can to be environmentally friendly.
 Avastin will be produced by Roche in Basel for the European market.
Avastin will be produced by Roche in Basel for the European market.
The new manufacturing building in Penzberg from the architects drawing side elevation.
The new manufacturing building in Penzberg from the architects drawing side elevation.
 Penzberg is situated in Southern Bavaria.
Penzberg is situated in Southern Bavaria.
 Herceptin will be among the drugs manufactured at the site.
Herceptin will be among the drugs manufactured at the site.
Breast cancer tumour cells under attack from Herceptin.
Breast cancer tumour cells under attack from Herceptin.
 Herceptin binds to the HER-2 receptors of breast cancer tumour cells.
Herceptin binds to the HER-2 receptors of breast cancer tumour cells.
 Thymoglobulin is used in transplantation but its uses are set to be extended.
Thymoglobulin is used in transplantation but its uses are set to be extended.
One of the indications for the drug is in the treatment of aplastic anaemia.
One of the indications for the drug is in the treatment of aplastic anaemia.
 Thymoglobulin has a protective effect against white blood cells in preventing rejection of the transplanted tissue in renal transplantation.
Thymoglobulin has a protective effect against white blood cells in preventing rejection of the transplanted tissue in renal transplantation.
 Thymoglobulin can help prevent acute rejection – one of the biggest problems in renal transplant.
Thymoglobulin can help prevent acute rejection – one of the biggest problems in renal transplant.
Thymoglobulin is administered by IV infusion.
Thymoglobulin is administered by IV infusion.
 An aerial view of AstraZeneca's new Avlon plant.
An aerial view of AstraZeneca's new Avlon plant.
 Molecular model of Rosuvastatin.
Molecular model of Rosuvastatin.
The new plant at Bristol actually consists of two manufacturing plants: a technology transfer plant and the new full-scale Crestor production plant.
The new plant at Bristol actually consists of two manufacturing plants: a technology transfer plant and the new full-scale Crestor production plant.
 Rosuvastatin calcium is the active pharmaceutical ingredient for the new once-per-day dyslipidaemia treatment Crestor.
Rosuvastatin calcium is the active pharmaceutical ingredient for the new once-per-day dyslipidaemia treatment Crestor.
 Atherosclerosis formation.
Atherosclerosis formation.
The Biberach site now has the largest R&D facility operated by Boehringer Ingelheim.
The Biberach site now has the largest R&D facility operated by Boehringer Ingelheim.
 The new integrated pharmaceutical building at Biberach incorporates state-of-the-art technology.
The new integrated pharmaceutical building at Biberach incorporates state-of-the-art technology.
 In 2008 the new Boehringer plant won the Facility of the Year award for the facility integration category.
In 2008 the new Boehringer plant won the Facility of the Year award for the facility integration category.
The Biberach plant is configured to handle highly potent compounds.
The Biberach plant is configured to handle highly potent compounds.
 Boehringer Ingelheim has now extended its research focus into oncology.
Boehringer Ingelheim has now extended its research focus into oncology.
 The new Pfizer facility is situated in Illertissen in the south of Germany.
The new Pfizer facility is situated in Illertissen in the south of Germany.
The active ingredient of Chantix, varenicline, is produced in Pfizer's Little Island plant in Ireland.
The active ingredient of Chantix, varenicline, is produced in Pfizer's Little Island plant in Ireland.
 Vareniciline acts on the nicotinic receptors.
Vareniciline acts on the nicotinic receptors.
 Nicotine is the addictive drug in tobacco, which causes smokers to continue the habit.
Nicotine is the addictive drug in tobacco, which causes smokers to continue the habit.
Pfizer's Chantix has been shown to be highly effective in patients wishing to give up tobacco smoking.
Pfizer's Chantix has been shown to be highly effective in patients wishing to give up tobacco smoking.
 A new facility for the production of live human viral vaccines was opened by IDT Biologika in May 2007.
A new facility for the production of live human viral vaccines was opened by IDT Biologika in May 2007.
 The IDT Biologika site has the capacity for the production of many different vaccines.
The IDT Biologika site has the capacity for the production of many different vaccines.
The majority of operations at the IDT Biologika facility are contained inside cleanrooms.
The majority of operations at the IDT Biologika facility are contained inside cleanrooms.
 The IDT Biologika facility will use downstream technology to develop vaccines against infectious diseases such as tuberculosis, malaria, AIDS and rotavirus.
The IDT Biologika facility will use downstream technology to develop vaccines against infectious diseases such as tuberculosis, malaria, AIDS and rotavirus.
 The facility's cleanrooms can culture viruses at a wide range of temperatures.
The facility's cleanrooms can culture viruses at a wide range of temperatures.
The process engineer for the IDT Biologica facility was BIDECO GmbH.
The process engineer for the IDT Biologica facility was BIDECO GmbH.
 The site at Fornovo San Giovanni will soon be expanded with a new API manufacturing plant.
The site at Fornovo San Giovanni will soon be expanded with a new API manufacturing plant.
 The plant is located in the Lombardy region of Italy and is centrally placed in Europe to supply other Boehringer Ingelheim affiliates with APIs.
The plant is located in the Lombardy region of Italy and is centrally placed in Europe to supply other Boehringer Ingelheim affiliates with APIs.
Bromination is one of the facility's areas of expertise.
Bromination is one of the facility's areas of expertise.
 The Bidachem plant produces a range of generic APIs including such compounds as ketoprofen and ibuprofen.
The Bidachem plant produces a range of generic APIs including such compounds as ketoprofen and ibuprofen.
 The plant can offer a range of services to third parties including laboratory trials and process development.
The plant can offer a range of services to third parties including laboratory trials and process development.
The CHF170m plant conversion completed in 1999 was designed for the first stages in the manufacture of the new-generation antihypertensive, Diovan and provides Novartis with an important platform for the future development and production of the drug.
The CHF170m plant conversion completed in 1999 was designed for the first stages in the manufacture of the new-generation antihypertensive, Diovan and provides Novartis with an important platform for the future development and production of the drug.
 Location of Novartis' Diovan production plant near Basel, Switzerland.
Location of Novartis' Diovan production plant near Basel, Switzerland.
 Rohner AG has unsurpassed expertise in the production of fine chemicals.
Rohner AG has unsurpassed expertise in the production of fine chemicals.
The Rohner Custom Synthesis Plant is situated in Pratteln near Basel, Switzerland.
The Rohner Custom Synthesis Plant is situated in Pratteln near Basel, Switzerland.
 Hydrogenation is one of the basic reaction types offered in custom synthesis at the Pratteln plant.
Hydrogenation is one of the basic reaction types offered in custom synthesis at the Pratteln plant.
 Grignard reactions are a basic organometallic reaction type undertaken at the Rohner plant.
Grignard reactions are a basic organometallic reaction type undertaken at the Rohner plant.
The Rohner Custom Synthesis Plant changed hands for the third time in 2006.
The Rohner Custom Synthesis Plant changed hands for the third time in 2006.
 The pharmaceuticals complex at Snackviken in Södartälje, Sweden.
The pharmaceuticals complex at Snackviken in Södartälje, Sweden.
 The investment was made due to growing demand for the company's range of asthmatic inhalers.
The investment was made due to growing demand for the company's range of asthmatic inhalers.
The new plant will manufacture the asthma treatments Pulmicort and Oxis.
The new plant will manufacture the asthma treatments Pulmicort and Oxis.
 Expanding capacity in existing plants is cheaper than building an entirely new plant.
Expanding capacity in existing plants is cheaper than building an entirely new plant.
 The Turbular product is a chlorofluorocarbon (CFC)-free, multidose dry-powder inhaler for asthmatic treatment.
The Turbular product is a chlorofluorocarbon (CFC)-free, multidose dry-powder inhaler for asthmatic treatment.
The project saw construction on the new plant begin in 2000.
The project saw construction on the new plant begin in 2000.
 Map showing location of Grimsby.
Map showing location of Grimsby.
 Model of Ringaskiddy plant.
Model of Ringaskiddy plant.
Ringaskiddy offices.
Ringaskiddy offices.
 Pfizer manufactures the active pharmaceutical ingredients for its Viagra pills at Ringaskiddy.
Pfizer manufactures the active pharmaceutical ingredients for its Viagra pills at Ringaskiddy.
 The OSP4 facility is capable of producing primary bulk, batch pharmaceutical products.
The OSP4 facility is capable of producing primary bulk, batch pharmaceutical products.
Finished goods building
Finished goods building
 Chemical structure of Sildenafil (Viagra).
Chemical structure of Sildenafil (Viagra).
 A Pharmacia & Upjohn facility in Uppsala
A Pharmacia & Upjohn facility in Uppsala
Fermentation vessels at Wyeth's biotechnology campus in Dublin. The campus will comprise three separate facilities - a drug development unit, a drug substance unit and a drug product facility.
Fermentation vessels at Wyeth's biotechnology campus in Dublin. The campus will comprise three separate facilities - a drug development unit, a drug substance unit and a drug product facility.
 Purification train at Wyeth's new biotechnology campus at the Grange Castle International Business Park in Clondalkin, Dublin, Ireland.
Purification train at Wyeth's new biotechnology campus at the Grange Castle International Business Park in Clondalkin, Dublin, Ireland.
 Examination of cell lines.
Examination of cell lines.
Pneumococcal bacterial culture.
Pneumococcal bacterial culture.
 Rheumatoid arthritis of the upper extremities.
Rheumatoid arthritis of the upper extremities.
 Location map of Hoechst´s Frankfurt Plant.
Location map of Hoechst´s Frankfurt Plant.
Janssen's Alzheimer's drug Galantamine was originally isolated from daffodil bulbs.
Janssen's Alzheimer's drug Galantamine was originally isolated from daffodil bulbs.
 Location map of Geel pharmaceutical raw material plant in Belgium.
Location map of Geel pharmaceutical raw material plant in Belgium.
 Galantamine (Reminyl structure).
Galantamine (Reminyl structure).
Reminyl, which has been marketed since 2002.
Reminyl, which has been marketed since 2002.
 Fentanyl administered as a transdermal patch.
Fentanyl administered as a transdermal patch.
 Location map of Biochem´s Frankfurt Plant.
Location map of Biochem´s Frankfurt Plant.
Innovo insulin dose injection system.
Innovo insulin dose injection system.
 Novopen insulin injection system.
Novopen insulin injection system.
 Novomix Flexpen insulin injection system.
Novomix Flexpen insulin injection system.
Filled insulin cartridges produced at the Chartres facility.
Filled insulin cartridges produced at the Chartres facility.
 Molecular diagram of insulin crystals produced from x-ray crystallographic data.
Molecular diagram of insulin crystals produced from x-ray crystallographic data.
 High resolution image of insulin crystals.
High resolution image of insulin crystals.
Engineering design for the new active ingredients plant.
Engineering design for the new active ingredients plant.
 Interior of the Boehringer Ingelheim plant.
Interior of the Boehringer Ingelheim plant.
 Biopharmaceutical production.
Biopharmaceutical production.
Construction of new active ingredients plant at Ingelheim.
Construction of new active ingredients plant at Ingelheim.
 The company has signed a loan agreement with the European Investment Bank (EIB).
The company has signed a loan agreement with the European Investment Bank (EIB).
 The exterior of the building.
The exterior of the building.
An interior image of the LSL showing one of the smaller scale reactors.
An interior image of the LSL showing one of the smaller scale reactors.
 Inside the LSL showing the containment fume cupboards.
Inside the LSL showing the containment fume cupboards.
 The LSL hydrogenation suite.
The LSL hydrogenation suite.
Pipework in one of the processing areas.
Pipework in one of the processing areas.
 Pfizer is to increase the number of biologics in its pipeline and is constructing manufacturing capacity.
Pfizer is to increase the number of biologics in its pipeline and is constructing manufacturing capacity.
 CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) targets T cells; an antibody to inhibit it is one of Pfizer's cancer therapies.
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) targets T cells; an antibody to inhibit it is one of Pfizer's cancer therapies.
Pfizer has been in the Cork area since 1969 and has a number of plants, employing a total of 2,200 personnel in Ireland.
Pfizer has been in the Cork area since 1969 and has a number of plants, employing a total of 2,200 personnel in Ireland.
 Torcetrapib is the anti cholesterol drug that Pfizer took out of Phase III clinical trials in December 2006.
Torcetrapib is the anti cholesterol drug that Pfizer took out of Phase III clinical trials in December 2006.
 Strangnas is in Sweden situated near Stockholm.
Strangnas is in Sweden situated near Stockholm.
The growth hormone molecule (polypeptide).
The growth hormone molecule (polypeptide).
 Growth hormone is produced in the pituitary gland.
Growth hormone is produced in the pituitary gland.
 The pituitary is a complex area of the brain and a lack of growth hormone production can lead to several serious conditions.
The pituitary is a complex area of the brain and a lack of growth hormone production can lead to several serious conditions.
The growth hormone Genotropin in the Strangnas facility is produced using recombinant DNA techniques.
The growth hormone Genotropin in the Strangnas facility is produced using recombinant DNA techniques.
 Aerial view of the new pharmaceutical bulk manufacturing plant.
Aerial view of the new pharmaceutical bulk manufacturing plant.
 The new plant during construction.
The new plant during construction.
The pharmaceutical production building at the new Bristol-Myers Squibb Cruiserath facility.
The pharmaceutical production building at the new Bristol-Myers Squibb Cruiserath facility.
 Reactor tops.
Reactor tops.
 Solvent recovery.
Solvent recovery.
An overview of the Merck plant at Ballydine.
An overview of the Merck plant at Ballydine.
 A chemist analysing a product sample in the Technical Operations Laboratory.
A chemist analysing a product sample in the Technical Operations Laboratory.
 The central control room in the Ballydine plant.
The central control room in the Ballydine plant.
Merck Sharp & Dohme's Facility in Ballydine - Ireland.
Merck Sharp & Dohme's Facility in Ballydine - Ireland.
 Chart showing health expenditure as a proportion of GDP.
Chart showing health expenditure as a proportion of GDP.
 Roche's new pharmaceutical manufacturing plant is located in Gebze, Turkey.
Roche's new pharmaceutical manufacturing plant is located in Gebze, Turkey.
Example of tablets to be produced at Gebze.
Example of tablets to be produced at Gebze.
 Example of solid dosage forms.
Example of solid dosage forms.
 Hard gelatine capsule, of the type that will be manufactured at Gebze.
Hard gelatine capsule, of the type that will be manufactured at Gebze.
The administrative building at Lundbeck's synthesis factory on Teesside, in north-east England.
The administrative building at Lundbeck's synthesis factory on Teesside, in north-east England.
 The tank farm at Lundbeck's escitalopram synthesis factory in north-east England.
The tank farm at Lundbeck's escitalopram synthesis factory in north-east England.
 The Seal Sands production site is equipped to produce escitalopram (the S enantiomer), a selective serotonin reuptake inhibitor that is marketed under the brand name Cipralex.
The Seal Sands production site is equipped to produce escitalopram (the S enantiomer), a selective serotonin reuptake inhibitor that is marketed under the brand name Cipralex.
Novasep simulated moving bed unit (Lico Sep 6-800).
Novasep simulated moving bed unit (Lico Sep 6-800).
 Work on the construction of the new production unit, which has been named P7, commenced in Seal Sands in May 2000.
Work on the construction of the new production unit, which has been named P7, commenced in Seal Sands in May 2000.
 Tank farm at the facility.
Tank farm at the facility.
Chemical structure of escitalopram (S enantiomer).
Chemical structure of escitalopram (S enantiomer).
 Polpharma's Dry Forms II plant is a secondary manufacturing facility for the production of tablets, capsules and effervescent tablets.
Polpharma's Dry Forms II plant is a secondary manufacturing facility for the production of tablets, capsules and effervescent tablets.
 The new pharmaceutical production facility in Starogard Gdanski, Poland.
The new pharmaceutical production facility in Starogard Gdanski, Poland.
The structure of one of Polpharma's drugs released in 2006, the antidepressant Sertralina.
The structure of one of Polpharma's drugs released in 2006, the antidepressant Sertralina.
 The structure of Risperidon.
The structure of Risperidon.
 The dry forms II plant produces medication such as Risperidon.
The dry forms II plant produces medication such as Risperidon.
Artist impression of Avecia Biotechnology's new Advanced Biologics Centre.
Artist impression of Avecia Biotechnology's new Advanced Biologics Centre.
Centrifuges are part of the downstream processing equipment.
Centrifuges are part of the downstream processing equipment.
Construction of the new Advanced Biologics Centre, day 126.
Construction of the new Advanced Biologics Centre, day 126.
Construction of the new Advanced Biologics Centre, day 233.
Construction of the new Advanced Biologics Centre, day 233.
Construction of the new Advanced Biologics Centre, day 29.
Construction of the new Advanced Biologics Centre, day 29.
Separation suite at the biologics manufacturing centre.
Separation suite at the biologics manufacturing centre.
Small 30 litre vessels.
Small 30 litre vessels.
Lantus fill and finish line.
Lantus fill and finish line.
 Lantus packet shot.
Lantus packet shot.
Nozzle and plate separators.
Nozzle and plate separators.
 15,000l bioreactor.
15,000l bioreactor.
 Clean room facility.
Clean room facility.
Visp small-scale production plant.
Visp small-scale production plant.
 Reactor in small-scale production plant.
Reactor in small-scale production plant.
 Filter drier in compliance with cGMP.
Filter drier in compliance with cGMP.
The Lonza Visp site covers a vast area and the API plant will give the company a new contract synthesis market to exploit.
The Lonza Visp site covers a vast area and the API plant will give the company a new contract synthesis market to exploit.
 Portsmouth is an important facility for Lonza as it is central to the US market.
Portsmouth is an important facility for Lonza as it is central to the US market.
 The expansion at Portsmouth is costing $300m.
The expansion at Portsmouth is costing $300m.
Eculizumab is a recent biologic treatment produced by Lonza for Alexion Pharmaceuticals.
Eculizumab is a recent biologic treatment produced by Lonza for Alexion Pharmaceuticals.
 Artist's impression of the new Ferring Pharmaceuticals production facility.
Artist's impression of the new Ferring Pharmaceuticals production facility.
 Ferring's new facility has four areas for production, packaging, storage and administration and covers 23,000m².
Ferring's new facility has four areas for production, packaging, storage and administration and covers 23,000m².
The new API and synthetic peptide facility will make extensive use of glass panels in its construction.
The new API and synthetic peptide facility will make extensive use of glass panels in its construction.
 Pentasa (mesalazine) is one of a new generation of drugs used in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease.
Pentasa (mesalazine) is one of a new generation of drugs used in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease.
 Molecular structure of 5-ASA.
Molecular structure of 5-ASA.
Yeast cells visualised with a fluorescent dye.
Yeast cells visualised with a fluorescent dye.
 Bacterial culture prior to inoculation to large-scale.
Bacterial culture prior to inoculation to large-scale.
 Checking DNA profile of new cell line.
Checking DNA profile of new cell line.
Artist's representation of new NBC.
Artist's representation of new NBC.
 Level 4 microbiological containment suits.
Level 4 microbiological containment suits.
 Layout of facility.
Layout of facility.
Location map of facility.
Location map of facility.
 Peptic ulcer drug Lansodin (lansoprazole).
Peptic ulcer drug Lansodin (lansoprazole).
 Location of Grange Castle International Business Park.
Location of Grange Castle International Business Park.
Pioglitazone chemical structure.
Pioglitazone chemical structure.
 Candesartan chemical structure.
Candesartan chemical structure.
 The new API plant, showing the landscaped grounds.
The new API plant, showing the landscaped grounds.
The new API plant from another angle.
The new API plant from another angle.
 Vaccine production plant bioreactors.
Vaccine production plant bioreactors.
Employee using Biosafety Level Three facilities in QA laboratory.
Employee using Biosafety Level Three facilities in QA laboratory.
InBatch control system showing information on screen.
InBatch control system showing information on screen.
Vibrio cholerae visualised with a red stain.
Vibrio cholerae visualised with a red stain.
Close up of the String Test used for acquiring a sample from a human to be tested for cholera.
Close up of the String Test used for acquiring a sample from a human to be tested for cholera.
Cholera cultured on agar plate.
Cholera cultured on agar plate.
Typical area for cholera contamination in South East Asia.
Typical area for cholera contamination in South East Asia.
SBL's Dukoral vaccine protects against E. Coli and cholera.
SBL's Dukoral vaccine protects against E. Coli and cholera.
The administrative block of Krka's new facility.
The administrative block of Krka's new facility.
The new Krka-Rus solid dosage forms facility.
The new Krka-Rus solid dosage forms facility.
A Kilian T-300-1 tableting machine.
A Kilian T-300-1 tableting machine.
One of the packaging lines at the new solid dosage forms production facility.
One of the packaging lines at the new solid dosage forms production facility.
A quality control laboratory technician.
A quality control laboratory technician.
Chemical structure of Choletar.
Chemical structure of Choletar.
Novo Nordisk's facility at Kalundborg produces more than 40% of the world's insulin.
Novo Nordisk's facility at Kalundborg produces more than 40% of the world's insulin.
The plant was built as modular 'skids' to exact specifications off-site while buildings were being constructed.
The plant was built as modular 'skids' to exact specifications off-site while buildings were being constructed.
The front of the facility showing part of the main building and the administration block.
The front of the facility showing part of the main building and the administration block.
An operator working on one of the fermentation vessels.
An operator working on one of the fermentation vessels.
A high resolution micrograph of purified insulin crystals.
A high resolution micrograph of purified insulin crystals.
Packaging of insulin pens at Kalundborg.
Packaging of insulin pens at Kalundborg.
Bavarian Nordic's new smallpox vaccine production facility is being set up to supply increased demand for smallpox vaccine around the world.
Bavarian Nordic's new smallpox vaccine production facility is being set up to supply increased demand for smallpox vaccine around the world.
 A vaccinia injection site reaction after two days.
A vaccinia injection site reaction after two days.
 Electron micrograph of smallpox virus.
Electron micrograph of smallpox virus.
Histological slide of skin affected by smallpox vaccination.
Histological slide of skin affected by smallpox vaccination.
 Necrotic skin reaction to traditional Vaccinia smallpox vaccination.
Necrotic skin reaction to traditional Vaccinia smallpox vaccination.
 Severe necrotic skin reaction to traditional Vaccinia smallpox vaccination.
Severe necrotic skin reaction to traditional Vaccinia smallpox vaccination.
The Bavarian Nordic MVA-BN third generation smallpox vaccine IMMAVUNE has been shown to have fewer side effects than traditional Vaccinia smallpox vaccines, such as Dryax.
The Bavarian Nordic MVA-BN third generation smallpox vaccine IMMAVUNE has been shown to have fewer side effects than traditional Vaccinia smallpox vaccines, such as Dryax.
Centocor's new biopharmaceutical manufacturing facility in Ringaskiddy, Republic of Ireland, will manufacture many of the company's existing and new pipeline recombinant mammalian cell fermentation and monoclonal antibody products.
Centocor's new biopharmaceutical manufacturing facility in Ringaskiddy, Republic of Ireland, will manufacture many of the company's existing and new pipeline recombinant mammalian cell fermentation and monoclonal antibody products.
 A section of the window cladding for the new biopharmaceutical manufacturing facility.
A section of the window cladding for the new biopharmaceutical manufacturing facility.
Section of lower colon showing ulceration from Crohn's disease.
Section of lower colon showing ulceration from Crohn's disease.
 Radiograph of a Crohn's diseased colon.
Radiograph of a Crohn's diseased colon.
 Remicade is indicated for the treatment of, among other things, rheumatoid arthritis nodules.
Remicade is indicated for the treatment of, among other things, rheumatoid arthritis nodules.
Rheumatoid arthritis nodules in the elbow, also treated by Remicade.
Rheumatoid arthritis nodules in the elbow, also treated by Remicade.
 The Turbuhaler, which has been the mainstay of dispensing pulmonary drugs for AstraZeneca, is to be superseded by pressurised metered dose inhalers.
The Turbuhaler, which has been the mainstay of dispensing pulmonary drugs for AstraZeneca, is to be superseded by pressurised metered dose inhalers.
 Diagram showing the differences between healthy and asthmatic lung tissue.
Diagram showing the differences between healthy and asthmatic lung tissue.
The molecular structure of the bronchodilator fromoterol, one of the active components of the combination therapy Symbicort.
The molecular structure of the bronchodilator fromoterol, one of the active components of the combination therapy Symbicort.
 The molecular structure of the corticosteroid budesonide, one of the active components of the combination therapy Symbicort.
The molecular structure of the corticosteroid budesonide, one of the active components of the combination therapy Symbicort.
 An electron micrograph of a healthy alveolus.
An electron micrograph of a healthy alveolus.
Rhodia Pharma Solutions' Annan facility has four independent pharmaceutical manufacturing and development buildings.
Rhodia Pharma Solutions' Annan facility has four independent pharmaceutical manufacturing and development buildings.
The facilities are being upgraded to provide new capacity for manufacturing scale, pilot scale and scale-up development for contract manufacturing.
The facilities are being upgraded to provide new capacity for manufacturing scale, pilot scale and scale-up development for contract manufacturing.
Rhodia Pharma Solutions carries out contracts for major pharmaceutical companies and also for smaller 'start-up' companies.
Rhodia Pharma Solutions carries out contracts for major pharmaceutical companies and also for smaller 'start-up' companies.
The Annan facility is cGMP validated and specialises in the production of bulk active pharmaceutical ingredients (API).
The Annan facility is cGMP validated and specialises in the production of bulk active pharmaceutical ingredients (API).
One of the new products being produced at Annan is WS-23, a flavour and fragrance building block specifically used in pharmaceutical products as a taste enhancer.
One of the new products being produced at Annan is WS-23, a flavour and fragrance building block specifically used in pharmaceutical products as a taste enhancer.
The plant also produces a range of APIs for use in the manufacture of a new drug to treat bone cancers.
The plant also produces a range of APIs for use in the manufacture of a new drug to treat bone cancers.
Gas chromatograph in the QC/QA department.
Gas chromatograph in the QC/QA department.
Ferring Pharmaceuticals has built a new pharmaceutical freeze drying and filling production facility near Kiel, Germany.
Ferring Pharmaceuticals has built a new pharmaceutical freeze drying and filling production facility near Kiel, Germany.
 The glass facade panels of the building's upper floor are specially designed with wing-like aluminium lamellae for sun and wind protection.
The glass facade panels of the building's upper floor are specially designed with wing-like aluminium lamellae for sun and wind protection.
The new freeze drying and filling facility will fill and freeze dry pharmaceutical products in accordance with the latest cGMP and US FDA regulations.
The new freeze drying and filling facility will fill and freeze dry pharmaceutical products in accordance with the latest cGMP and US FDA regulations.
 The new plant will freeze-dry and fill some of Ferring's most successful products, including Bravelle, a highly purified preparation of human follicle stimulating hormone (FSH).
The new plant will freeze-dry and fill some of Ferring's most successful products, including Bravelle, a highly purified preparation of human follicle stimulating hormone (FSH).
 The Altana pharmaceutical plant under construction.
The Altana pharmaceutical plant under construction.
The finished Altana pharmaceutical building,
The finished Altana pharmaceutical building,
 Pantoprazole is one of the most successful drugs ever to have come out of a German laboratory.
Pantoprazole is one of the most successful drugs ever to have come out of a German laboratory.
 Roflumilast has enormous potential for the treatment of COPD and Asthma.
Roflumilast has enormous potential for the treatment of COPD and Asthma.
Elan Pharma is constructing a new sterile fill and finish pharmaceutical facility at its Athlone site in the Republic of Ireland.
Elan Pharma is constructing a new sterile fill and finish pharmaceutical facility at its Athlone site in the Republic of Ireland.
 The new secondary pharmaceutical facility will be used for the production of oral solid dosage forms and also for the filling of vials.
The new secondary pharmaceutical facility will be used for the production of oral solid dosage forms and also for the filling of vials.
 The secondary pharmaceutical facility is a steel-framed, cladded, three-floor building, with an adjoining single-storey warehouse.
The secondary pharmaceutical facility is a steel-framed, cladded, three-floor building, with an adjoining single-storey warehouse.
The cleanroom design includes several full-height glass walls on a circulation corridor around the processing floor and two 'inspection' corridors with full-length glass walls.
The cleanroom design includes several full-height glass walls on a circulation corridor around the processing floor and two 'inspection' corridors with full-length glass walls.
 One of the new drugs to be filled and finished at the new facility will be the capsule form of Duloxetine Hydrochloride (Cymbalta, Xeristar).
One of the new drugs to be filled and finished at the new facility will be the capsule form of Duloxetine Hydrochloride (Cymbalta, Xeristar).
 The molecular structure of Duloxetine which is manufactured by Elan.
The molecular structure of Duloxetine which is manufactured by Elan.
Boehringer Ingelheim's Vienna facility is for the manufacture of therapeutically active proteins, plasmid DNA (pDNA) and single chain antibodies.
Boehringer Ingelheim's Vienna facility is for the manufacture of therapeutically active proteins, plasmid DNA (pDNA) and single chain antibodies.
 The company is capable of producing pDNA on a large scale, and at current Good Manufacturing Practice (cGMP) compliant levels.
The company is capable of producing pDNA on a large scale, and at current Good Manufacturing Practice (cGMP) compliant levels.
 Boehringer Ingelheim developed the CIM Technology in conjunction with BIA Separations and will now offer the technology as a Contract Manufacturing Organisation (CMO) service to customers worldwide.
Boehringer Ingelheim developed the CIM Technology in conjunction with BIA Separations and will now offer the technology as a Contract Manufacturing Organisation (CMO) service to customers worldwide.
The expansion of the Vienna facility has required a total investment of more than €80 million. It is the company’s largest single investment at its Austrian subsidiary.
The expansion of the Vienna facility has required a total investment of more than €80 million. It is the company’s largest single investment at its Austrian subsidiary.
 CIM tube monolithic columns are large-scale forms of CIM supports intended for laboratory, semi-industrial, and industrial scale purification and bioconversion.
CIM tube monolithic columns are large-scale forms of CIM supports intended for laboratory, semi-industrial, and industrial scale purification and bioconversion.
 Nexhet Kondirolli, with the help of European, USAID and venture capital funding, has been constructing a new pharmaceutical facility to supply much needed medicines to Kosovo.
Nexhet Kondirolli, with the help of European, USAID and venture capital funding, has been constructing a new pharmaceutical facility to supply much needed medicines to Kosovo.
Generic pills and capsules will be manufactured at the new facility. The plant will have four production lines and two shifts, with 75 employees and an annual output of 5 million units.
Generic pills and capsules will be manufactured at the new facility. The plant will have four production lines and two shifts, with 75 employees and an annual output of 5 million units.
 The 32,000ft² plant was structurally complete by the end of 2005 and will undergo stringent commissioning and qualification process which will lead to Good Manufacturing Practice (GMP) and European Quality standards being achieved.
The 32,000ft² plant was structurally complete by the end of 2005 and will undergo stringent commissioning and qualification process which will lead to Good Manufacturing Practice (GMP) and European Quality standards being achieved.
 Cough syrups will be produced and bottled at the new facility.
Cough syrups will be produced and bottled at the new facility.
Generic pharmaceuticals such as Aspirin (acetylsalicylic acid) will also play a big role in the product range.
Generic pharmaceuticals such as Aspirin (acetylsalicylic acid) will also play a big role in the product range.
 Aerial view of the Loughbeg manufacturing facility.
Aerial view of the Loughbeg manufacturing facility.
 A cholesterol molecule.
A cholesterol molecule.
Lipitor in blister pack form.
Lipitor in blister pack form.
 A Lipitor molecule.
A Lipitor molecule.
 Lipitor in tablet form.
Lipitor in tablet form.
Lipitor is a treatment for lowering cholesterol.
Lipitor is a treatment for lowering cholesterol.
 Refrigeration equipment installed at the production plant.
Refrigeration equipment installed at the production plant.
 BioSilicon electronmicrograph surface view.
BioSilicon electronmicrograph surface view.
BioSilicon honeycomb structure.
BioSilicon honeycomb structure.
 Syringe with BioSilicon material dissolved in transport medium.
Syringe with BioSilicon material dissolved in transport medium.
 Liver tumour in a computerised tomography scan.
Liver tumour in a computerised tomography scan.
Liver tumour cells.
Liver tumour cells.
 Map of Belgium demonstrating where the facility is located.
Map of Belgium demonstrating where the facility is located.
 A Gaucher cell typical of the disease.
A Gaucher cell typical of the disease.
Aldurazyme – a treatment for mucopolysaccharidosis I, produced by Genzyme.
Aldurazyme – a treatment for mucopolysaccharidosis I, produced by Genzyme.
 Renagel – a calcium free phosphate binder produced by Genzyme.
Renagel – a calcium free phosphate binder produced by Genzyme.
 The histology of Pompe disease.
The histology of Pompe disease.
Copyright Notice: Copyright for all images on this web site is held by the individual companies providing material for the site. Click on the image concerned to be taken through to the project, containing information on the company involved.


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