South Asia and Australasia
| Affymetrix Inc, Manufacturing Facility | ||
Affymetrix was one of the main developers of genetic microarray technology in the 1980s. |
The new Affymetrix manufacturing facility is in Singapore. |
GeneChips are produced on a quartz glass substrate. |
DNA microarrays allow thousands of experiments to be carried out at once. |
Affymetrix has partnered with 11 different companies to develop diagnostic tests. |
The purchase of an existing building in Singapore has helped to quickly provide a supporting manufacturing facility for Sacramento. |
| Aventis Enoxaparin Sodium Manufacturing Plant, | ||
Aventis's Jurong Island facility was opened in July 1999 to meet the growing world demand for enoxaparin sodium. |
First approved in France in 1987, enoxaparin is marketed in Europe as Clexane. |
Enoxaparin is marketed in the US as Lovenox. |
The drug is used to treat 108 million patients worldwide for deep vein thrombosis, unstable angina and non Q wave myocardial infarction. |
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| Bharat Biotech, Vaccine Production Plant, Perak | ||
The new plant will be outfitted with a range of fermentation and process vessels. |
Media preparation and weighing area. |
The surface of the Hepatitis B virus. |
A map of Perak where the new plant is being developed in a specialist pharmaceutical park. |
Two of Bharat Biotech’s products, Typbar typhoid vaccine and Regen-D healing ointment. |
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| Biopolis | ||
The Biopolis is a development for biomedical sciences R&D in Singapore. |
The third phase will add a further 41,505m² of space for rent to biomedical and pharmaceutical companies. |
The Biopolis phase III development will be completed by the end of 2009. |
The One-North development has 183ha for development in the LifeXchange region of the park. |
Biopolis hopes to unite educational and public research establishments with companies. |
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| CSL Recombinant Proteins Production Plant, | ||
Location of the Parkville vaccines plant in Australia. |
Fluorescent image of influenza virus. |
Blood agar culture of influenza virus. |
CSL has signed a five-year contract to supply influenza vaccine (FLUVAX) to northern hemisphere countries. |
Avonex for the treatment of MS. |
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| Genentech Singapore Biologics Plant | ||
Genentech, a subsidiary of Roche, has purchased the Longa plant in Singapore to merge with its own biologics facility. |
The merged plants will focus on producing drugs for the treatment of age-related macular degeneration. |
The combined facility is situated in Singapore's Tuas Biomedical Park, a hub for pharmaceutical and medical activity. |
Genentech's 1,000l E. coli manufacturing plant will produce Lucentis. |
The facility will manufacture Avastin (bevacizumab) and Herceptin. |
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| GlaxoSmithKline Vaccine Manufacturing Facility, Tuas | ||
GSK is investing $2bn in vaccine development. |
Singapore is training 1,000 new researchers and 100 PhDs over the next five years. |
Once merely a swamp, Tuas is now a burgeoning industrial area with many biopharma and pharma companies. |
The Tuas area of Singapore Island, where the vaccine plant is situated. |
Singapore is an economic success story with pharmaceuticals making up 16% of the country's manufacturing output. |
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| IC Asia Pharmaceutical Plant, | ||
Artist's impression of the new IC Asia facility. |
The pharmaceuticals plant was completed in early 2001. |
The new IC Asia plant is located just North of Ho Chi Minh City in Vietnam. |
| Merck Sharpe & Dohme Formulation Plant, | ||
MSD facility at Tuas Biomedical Park, Singapore. |
Tuas Park area map. |
Zocor - being used in a 'cholesterol-busting' combination treatment. |
Singulair - being used in a combination asthma and hayfever treatment. |
Simvastatin chemical structure. |
An atherosclerotic aorta caused by high cholesterol that may be prevented with the new combination treatment. |
| Novartis Biomanufacturing Plant, | ||
Tekturna will be one of the well-known Novartis medications produced at the new Tuas plant. |
Diovan will also be produced for the Asian, US and Middle Eastern markets by Novartis. |
The new Novartis plant will produce a range of drugs for treating hypertension. |
Tuas is an area in Singapore undergoing much development and so is ideal for major companies such as Novartis to increase their Asia Pacific presence. |
Singapore is rapidly growing as an industrial hub for many industries, including pharmaceuticals and biopharma. |
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| Novavax and CPL Biologicals Influenza Vaccine Manufacturing Facility | ||
Novavax and CPL Biologicals' Indian new facility will manufacture vaccines for the prevention of influenza. |
The CPL Biologicals joint venture plant uses VLP vaccine techniques, which means a vaccine can be produced using only a genetic sequence of a virus. |
Pandemic influenza strains such as H1N1 swine flu require the use of VLP technology to produce a large amount of vaccine in a short time. |
| Penang Biotech Park, Bukit Minyak | ||
The new Alpha Biologics facility in Malaysia. |
The Progenix facility will have its own primate building. |
The new facilities are in the Bukit Minyak region on the north western coast of the peninsular. |
Malaysia is trying to reinvent itself as a major biotech hub in Southeast Asia. |
The production from the Alpha Biologics facility will be based on mammalian cell lines. |
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| PerkinElmer Centre of Excellence | ||
Radionucleaotides are being produced at the new PerkinElmer centre of excellence in Singapore. |
PerkinElmer hopes that the new CoE will aid its pioneering drug discoveries. |
The centre of excellence is the second Singapore-based facility of its kind opened by PerkinElmer in the past year. |
| Pfizer Bulk Pharmaceutical Facility, | ||
Singapore is a strategically located port. The Singaporean government hopes to use the country's strategic position to exploit export markets in Asia. |
Pie chart showing health expenditure as a percentage of GDP. |
RSP Architects and Engineers of Singapore were also given a contract to take part in the design of the facility. |
The new facility is expected to come into operation in 2004. The total cost of the project is believed to be $340m. |
Nova Weigh equipment for use with intermediate bulk containers (IBCs). |
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| Pfizer Manufacturing Facility, | ||
The Dalian plant in China was officially opened in February 2009 in the Liaoning Province in China. |
The plant at Pfizer's Dalian site was the first GMP-certified plant in China. |
Dalian is being put forward as a new global-scale production plant for Pfizer. |
The new manufacturing plant will triple the doses produced of cephalosporin to 17 million vials a year. |
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| Protchem Derivatives Plant, | ||
Part of Protchem derivatives plant in Kodambakkam, India. |
A molecular model of Cysteine, one of the pharmaceutical derivatives produced at the plant. |
Map of India showing Chennai and Pondicherry on the east coast - locations of Protochem Industries' sites. |
| Schering-Plough Production and R&D Facilities, | ||
Schering Plough's biotechnology facility in Tuas, Singapore. |
The MPP1 plant produces loratadine and mometasone furoate. |
Glove box use in clean room suite. |
Separation facilities. |
Quality control (QC). |
Clean room suite for sterile product finishing. |
| Solagran Ltd, Biotech Plant, | ||
The Tomsk Special Economic Zone is in the middle of Siberia. |
Pine needles will be the main feedstock for the Solagran plant in Tomsk. |
Siberia has massive pine resources for the new Solagran plant and its larger successor. |
Polyprenols are made up of isoprene units and are almost impossible to synthesise in the laboratory. |
Some of the useful polyprenols could be extracted from pine resin, to produce Solagran's range of natural pharmaceuticals known as 'Bioeffectives'. |
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