MUnit, JETPHARMA, Microchem Micronisation of APIs, Excipients, Steroids, Cytotoxics, Cytostatics, HPAIs, and Antibiotics

Contract micronisation services

JETPHARMA (JP) and MICROCHEM (MCH) provide contract micronisation services to the pharmaceutical industry.

Founded in the 1960s by Alberto Martinoli, the companies have built a loyal and frequent customer base in the industry, developing their expertise with active pharmaceutical ingredients (API), inert substances, highly potent active ingredients (HPAI), cytotoxic and cytostatic drugs, steroids, and psychotropic substances.

They have achieved ever-increasing micronisation yields and ever-decreasing particle sizes, down to fractions of a micron.

In 2016, JP and MCH’s commercial and technical expertise were concentrated into new consultancy company MUnit. The group has developed a reputation for outstanding micronisation competence and excellent service levels.

Fully contained micronisation services

JP and MCH provide a range of services for micronisation under containment to avoid cross-contamination and mix-ups, prevent the release of hazardous substances into the environment, and protect the active ingredients and operators.

JP’s Glove box and Half-Suite box isolators allow high-containment performance below 25ng/m³ (third party verified). Its flexible and dependable operations mean up to 120l of product can be handled and packaged quickly and efficiently.

The isolator can be used with different types and sizes of mill, handling a variety of activities including jet milling, sieving, pin milling, and particle size distribution (PSD) analysis.

High-performance, scalable micronisation solutions

JP and MCH offer excellent scalability, with the ability to maintain the same granulometric curve at ever-increasing production capacities.

Using a series of modular machines, the companies can micronize single gram quantities up to hundreds of kilograms, while retaining the same granulometry and performance.

Strong regulatory success

JP and MCH have built an excellent reputation with regulatory authorities, including:

  • Swissmedic and European Medicines Authority (EMa), regularly inspected
  • US Food and Drug Administration (FDA) inspected pre-approval and good manufacturing practices (GMP)
  • Ministry of Health, Labor, and Welfare Japan (MHLW)

Mechanical milling services, de-lumping, API, excipient blending, and cryogenic micronisation

JP and MCH’s service range includes:

  • Micronisation of APIs, steroids, cytotoxics and cytostatics, HPAIs, antibiotics (not Beta-lactams) with its spiral jet mills (MC JETMILL)
  • Reduced product build-up and yields of more than 99% for the industrial process in quantities from 1kg upwards
  • Very fine and precise particle size distribution with just a single micronisation passage for almost all pharmaceutical ingredients
  • Micronisation of any pharmaceutical ingredients with no heat generation, even for those with a low (30°C – 40°C) melting poin, using isothermal jet mills
  • Mechanical milling services with a hammer mill and micronisation with jet mills
  • De-lumping, including the removal of agglomerates, can be achieved using spiral jet mills and a hammer mill
  • Dispensing and re-packing of bulk APIs into any sized container in our cleanrooms and / or isolators
  • Packaging under an inert atmosphere (nitrogen or argon) ensures API integrity through the preservation of powder
  • Blending of excipients and APIs is available as a standalone process or as part of a wider micronisation process
  • Sieving can also be provided as a standalone or combined process to achieve a specific particle size profile
  • Co-micronisation, which combines blending and particle size reduction of an API and / or excipient, is also available as a single process
  • Cryogenic micronisation is available for highly sensitive products, as it avoids polymorphic changes and an increase in amorphous particles; it is also enabling the micronisation of polymers

Laboratory activities and instruments for quality control

JP and MCH also offer a range of laboratory services for quality control purposes. These include:

  • Identification analysis
  • Cleaning validation studies
  • Particle size distribution analysis
  • Environment, water, and equipment surface microbiological monitoring
  • Analytical method transfer
  • Analytical method comparison study
  • Contract laboratory for PSD analysis

To ensure exceptional levels of quality control, the companies also have an extensive range of advanced laboratory instruments and equipment. These include:

  • Malvern Mastersizer Microplus (wet dispersion only)
  • Malvern Mastersizer 3000 (wet and dry dispersion)
  • Sympatec
  • Fourier transform infrared (FT-IR)
  • Melting point analyser
  • Ultraviolet (UV) visual spectrophotometer
  • Air sampler for microbiological analysis
  • Air sampler for environment hygiene control
  • Optical microscope with image analysis
  • Validation services for regulatory compliance

In addition, JP and MCH undertake a range of validation activities. These include:

  • Process parameter studies to define and support the validation activity
  • Process validation
  • Analytical method validation
  • Analytical method correlation study

To find out more or to make an enquiry, please contact MUnit, which operates as a single access point to all of JP and MCH services.

Make an enquiry

Press Release

MUNIT Attending DDL

MUnit is exhibiting at the forthcoming Drug Delivery to the Lungs (DDL) conference at Edinburgh International Conference Centre.

Product and Services
White Papers

State of Art in Micronisation

The real added value when managing the micronisation process of an API is the experience acquired in the field.


Via Crocicchio Cortogna 6

CH-6900 Lugano


+41 91 910 30 80

MUnit, JETPHARMA, Microchem Images

Related Projects

Press Release

30 November 2018

MUnit is exhibiting at the forthcoming Drug Delivery to the Lungs (DDL) conference at Edinburgh International Conference Centre.

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29 October 2018

MUNIT has announced it will be participating at the 5th Annual Controlled & Modified Drug Release Summit in Philadelphia, US.

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23 October 2018

MUNIT has announced that it will be participating at the 6th Annual World HPAPI congress in Basel, Switzerland.

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2 October 2018

MUnit, JETPHARMA and Microchem have announced they will be attending this year’s CPhI Woldwide and the co-located events ICSE, InnoPack, P-MEC and FDF.

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31 August 2018

MUNIT and its affiliates JETPHARMA and MICROCHEM are delighted to be a sponsor at the 8th American DDF Summit in San Francisco.

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16 August 2018

MUNIT is pleased to participate once again at the ChemOutsourcing event for pharmaceutical professionals.

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17 April 2018

MUnit has announced it will be showcasing its products at the Respiratory Drug Delivery (RDD) Conference at the JW Marriott in Tuscan, Arizona.

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11 April 2018

CPhI Japan is primarily a platform to establish new business relationships between European and Asian global pharmaceutical companies.

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3 April 2018

Munit has announced it will be participating as an exhibitor at the 4th Annual Formulation & Drug Delivery Congress in London, UK.

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20 March 2018

JP and MCH have announced they will be showcasing products at the 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology in Granada, Spain.  

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8 March 2018

MUnit has announced it will be attending the 9th Global Drug Delivery & Formulation Summit in Berlin, Germany.

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8 February 2018

MUnit is glad to announce its participation in the forthcoming DCAT. The exhibition will take place in New York from 19 to 22 March 2018.

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12 September 2017

MUNIT has announced its commercial director Mr Schiavazzi will be attending PharmaChemOutsourcing at Long Branch, New Jersey.

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4 May 2016

Jetpharma will be attending the 2nd Annual Formulation & Drug Delivery Congress in London, UK.

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15 March 2016

Jetpharma will be attending the 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology from 4-7 April in Glasgow.

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19 May 2015

Jetpharma's services continue to grow and the company is proud to announce a new range of services through the installation of Sympatec Helos BR.

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17 April 2015

Jetpharma will attend CPhI Japan at the Big Sight Exhibition Center in Tokyo, Japan.

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30 March 2015

Jetpharma has successfully installed a new pin mill within the Cytotoxic compounds facility.

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Regional Offices


Via Crocicchio Cortogna 6

CH-6900 Lugano


+41 91 910 30 80

Via Sottobisio 42a/c

P.O. Box 234

CH-6828 Balerna


+41 91 696 10 10 +41 91 696 10 30

Via Turati 2

I-29017 Fiorenzuola d'Arda (PC)


+39 0523 981 130

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