Sheffield Bio-Science Pharmaceutical Excipient Experts
For more than 65 years, Sheffield has earned its reputation as a successful world-class pharmaceutical supplier that demonstrates excellence in consistent, high-yielding, customer-specific solutions for the biotech and pharmaceutical markets. Sheffield Bio-Science has a rich history of leadership in providing the highest-quality excipient solutions that exceed customer expectations every day.
As part of the Kerry Group, a $6 billion leader, Sheffield Bio-Science can provide global technical service, and regulatory and application support, whether this is in the development process or trouble-shooting commercial production challenges.
Monohydrate and anhydrous lactose NF
Sheffield Bio-Science manufactures both the monohydrate and anhydrous forms of lactose, which meet NF / JP / EP monographs in a variety of particle sizes and are produced at a fully compliant FDA registered drug establishment in Norwich, NY, US. Assuring further consumer safety, all ingredients are certified rennet free.
Our lactose is used in a wide variety of product applications, including:
- Direct compression – anhydrous milled and sieved lactose
- Wet granulation and capsules – monohydrate milled and sieved lactose
- Micronized drug carrier – inhalation milled and sieved lactose
Lactose anhydrous DT – direct tabletting
Sheffield brand anhydrous lactose, NF – direct tabletting is the original patented formulation that is the most outstanding and unique direct compression excipient available. It features exceptional tabletting properties and offers many distinct advantages over other direct compression products, including:
- Superior tablet hardness at low compaction pressures
- Low friability
- Excellent dissolution
- Moisture stability
- Minimal color development
- Direct reworking ability
Lactose anhydrous DT high velocity
Lactose anhydrous NF high velocity direct tabletting, commonly referred to as lactose DTHV, has been specifically developed as a faster flowing form of lactose for high-speed direct tabletting operations. It has superior flowability and improved tablet uniformity, while maintaining tablet hardness at low compaction pressures when compared with traditional direct tabletting anhydrous lactose. It also retains the fast disintegration properties of anhydrous lactose. Additional advantages are low friability, improved moisture stability, reduced color development and improved reworking.
Tabletting systems
Sheffield tabletting system ODT is designed for use in orally disintegrating tablets. It can be blended with a flavor and active, or a taste-masked active and then directly compressed into tablets. It can also be used for tablets where dissolution is an issue when using typical excipients such as lactose or MCC.
Sheffield tabletting systems DTFD and DTHV are designed for use in tablets where a hard tablet with fast dissolution is desired. They are specially processed lactose-based products priced similarly to that of MCC, but with a faster dissolution rate. The tablet hardness and friability are similar to that of pure lactose.
Tablet coating systems
SheffCoat coating systems are an alternative and cost-effective pharmaceutical line of clear and colored film coatings. Sheffield Bio-Science has created a one step, ready-to-use system to match your existing coating and color, while offering a full spectrum of best-in-class, cost-effective solutions.
SheffCoat coating systems are based on well-known, pharmaceutically-accepted polymers, pigments and plasticizers and formulated to be compatible with any coating equipment. Not only can we streamline your supply chain, but you will also benefit from innovative ways to improve cost, speed and quality of tabletting.
Flavor modulators
Kerry, through its business group Sheffield, has created functionally specific flavor modulation technology (fmt) that is intended for use in the pharmaceutical market, particularly in the consumer-driven OTC segment. The flavor modulators can be used in both liquid and solid dosage forms, and work to improve consumer acceptance and patient compliance from the taste perspective.
Flavor modulation technology (fmt) is based on analytical and sensory findings of various components from natural sources. These flavor modulators provide the perception of sweetness and flavor enhancement to more effectively mask the bitter taste of an API. Kerry’s flavor modulation technology (fmt) leads to better overall flavor and sweetness perception to achieve a pleasant tasting drug delivery vehicle, which could not be achieved by simply overpowering the bitter API with flavor or sweeteners alone.
Kerry also has a standard collection of flavors for pharmaceutical applications. All the flavors in our standard collection have a DMF number.
Lactose for high-speed direct tabletting operations
Foremost brand 316 Fast Flo® lactose was specifically developed for use in high-speed direct tabletting operations. It contains a mixture of both crystalline and amorphous lactose. The special processing and particle size of the product aids in compressibility, flowability and disintegration, when compared with crystalline alpha monohydrate lactose.
Foremost Farms® USA and Sheffield have a strategic alliance for lactose marketing. Sheffield is a Kerry Group business. Sheffield manages the sales, marketing and distribution of Foremost Farms’ line of pharmaceutical lactose.
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Sheffield Bio-Science continues a reputation of excellence in providing pharmaceutical-grade lactose excipients, tabletting systems, coatings and flavours for drug delivery systems. As part of the Kerry Group, Sheffield Bio-Science has a history of leadership in providing the highest quality exci
Read moreSheffield Bio-Science has won the 2010 Frost & Sullivan Global new product innovation award in the pharmaceutical excipients market. The company's LubriTose product was singled out by the world-renowned consulting and research firm for improving the speed, quality and cost of tablet manufactu
Read moreSheffield Bio-Science, a leading global pharmaceutical supplier of superior quality cell nutrition and excipient products for the biotech and pharmaceutical markets, has been awarded the distinguished 2010 Lilly Global Supplier Award. The Lilly Global Supplier Award recognizes Sheffie
Read moreSheffield Bio-Science has launched a new brand identity and website to match its industry-leading products, technical expertise and global resources. For more than 65 years, Sheffield has earned its reputation as a successful world-class pharmaceutical supplier that demonstrates excelle
Read moreSheffield Bio-Science and Foremost Farms USA have announced a long-term manufacturing agreement that includes a joint investment to expand production of pharmaceutical lactose at Foremost Farms' Rothschild plant. With both companies recognised individually as market leaders, this agreem
Read moreVisit us at stand 6G48 at CPhI Worldwide 2009 at Fiera de Madrid, Spain, 13-15 October. This year we will be showcasing Kerry flavor modulator technology (fmt™), which provides the perception of sweetness and flavor enhancement to more effectively mask the bitter taste of an API. Read more
Leading pharmaceutical excipient producers, Kerry Bio-Science Sheffield™ Pharma Ingredients and Foremost Farms USA® announced today that they have formed a strategic marketing alliance which will significantly strengthen their combined market positions. Effective from January 1, 2007, t
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