Sheffield Bio-Science Pharmaceutical Excipient Experts

For more than 65 years, Sheffield has earned its reputation as a successful world-class pharmaceutical supplier that demonstrates excellence in consistent, high-yielding, customer-specific solutions for the biotech and pharmaceutical markets. Sheffield Bio-Science has a rich history of leadership in providing the highest-quality excipient solutions that exceed customer expectations every day.

As part of the Kerry Group, a $6 billion leader, Sheffield Bio-Science can provide global technical service, and regulatory and application support, whether this is in the development process or trouble-shooting commercial production challenges.

Monohydrate and anhydrous lactose NF

Sheffield Bio-Science manufactures both the monohydrate and anhydrous forms of lactose, which meet NF / JP / EP monographs in a variety of particle sizes and are produced at a fully compliant FDA registered drug establishment in Norwich, NY, US. Assuring further consumer safety, all ingredients are certified rennet free.

Our lactose is used in a wide variety of product applications, including:

  • Direct compression – anhydrous milled and sieved lactose
  • Wet granulation and capsules – monohydrate milled and sieved lactose
  • Micronized drug carrier – inhalation milled and sieved lactose

Lactose anhydrous DT – direct tabletting

Sheffield brand anhydrous lactose, NF – direct tabletting is the original patented formulation that is the most outstanding and unique direct compression excipient available. It features exceptional tabletting properties and offers many distinct advantages over other direct compression products, including:

  • Superior tablet hardness at low compaction pressures
  • Low friability
  • Excellent dissolution
  • Moisture stability
  • Minimal color development
  • Direct reworking ability

Lactose anhydrous DT high velocity

Lactose anhydrous NF high velocity direct tabletting, commonly referred to as lactose DTHV, has been specifically developed as a faster flowing form of lactose for high-speed direct tabletting operations. It has superior flowability and improved tablet uniformity, while maintaining tablet hardness at low compaction pressures when compared with traditional direct tabletting anhydrous lactose. It also retains the fast disintegration properties of anhydrous lactose. Additional advantages are low friability, improved moisture stability, reduced color development and improved reworking.

Tabletting systems

Sheffield tabletting system ODT is designed for use in orally disintegrating tablets. It can be blended with a flavor and active, or a taste-masked active and then directly compressed into tablets. It can also be used for tablets where dissolution is an issue when using typical excipients such as lactose or MCC.

Sheffield tabletting systems DTFD and DTHV are designed for use in tablets where a hard tablet with fast dissolution is desired. They are specially processed lactose-based products priced similarly to that of MCC, but with a faster dissolution rate. The tablet hardness and friability are similar to that of pure lactose.

Tablet coating systems

SheffCoat coating systems are an alternative and cost-effective pharmaceutical line of clear and colored film coatings. Sheffield Bio-Science has created a one step, ready-to-use system to match your existing coating and color, while offering a full spectrum of best-in-class, cost-effective solutions.

SheffCoat coating systems are based on well-known, pharmaceutically-accepted polymers, pigments and plasticizers and formulated to be compatible with any coating equipment. Not only can we streamline your supply chain, but you will also benefit from innovative ways to improve cost, speed and quality of tabletting.

Flavor modulators

Kerry, through its business group Sheffield, has created functionally specific flavor modulation technology (fmt™) that is intended for use in the pharmaceutical market, particularly in the consumer-driven OTC segment. The flavor modulators can be used in both liquid and solid dosage forms, and work to improve consumer acceptance and patient compliance from the taste perspective.

Flavor modulation technology (fmt) is based on analytical and sensory findings of various components from natural sources. These flavor modulators provide the perception of sweetness and flavor enhancement to more effectively mask the bitter taste of an API. Kerry’s flavor modulation technology (fmt) leads to better overall flavor and sweetness perception to achieve a pleasant tasting drug delivery vehicle, which could not be achieved by simply overpowering the bitter API with flavor or sweeteners alone.

Kerry also has a standard collection of flavors for pharmaceutical applications. All the flavors in our standard collection have a DMF number.

Lactose for high-speed direct tabletting operations

Foremost™ brand 316 Fast Flo® lactose was specifically developed for use in high-speed direct tabletting operations. It contains a mixture of both crystalline and amorphous lactose. The special processing and particle size of the product aids in compressibility, flowability and disintegration, when compared with crystalline alpha monohydrate lactose.

Foremost Farms® USA and Sheffield have a strategic alliance for lactose marketing. Sheffield is a Kerry Group business. Sheffield manages the sales, marketing and distribution of Foremost Farms’ line of pharmaceutical lactose.

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Press Release

Pharmaceutical Excipient Experts Sheffield™ to Exhibit at CPhI Worldwide 2010

Sheffield Bio-Science continues a reputation of excellence in providing pharmaceutical-grade lactose excipients, tabletting systems, coatings and flavours for drug delivery systems. As part of the Kerry Group, Sheffield Bio-Science has a history of leadership in providing the highest quality exci

Address
Sheffield Bio-Science,

Americas Regional Office

158 State Highway 320

Norwich, NY 13815

Other

United States of America

+1 800 833 8308 +1 607 334 5022 www.sheffieldbioscience.com

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Press Release

28 September 2010

Sheffield Bio-Science continues a reputation of excellence in providing pharmaceutical-grade lactose excipients, tabletting systems, coatings and flavours for drug delivery systems. As part of the Kerry Group, Sheffield Bio-Science has a history of leadership in providing the highest quality exci

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12 July 2010

Sheffield Bio-Science has won the 2010 Frost & Sullivan Global new product innovation award in the pharmaceutical excipients market. The company's LubriTose product was singled out by the world-renowned consulting and research firm for improving the speed, quality and cost of tablet manufactu

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12 July 2010

Sheffield Bio-Science, a leading global pharmaceutical supplier of superior quality cell nutrition and excipient products for the biotech and pharmaceutical markets, has been awarded the distinguished 2010 Lilly Global Supplier Award. The Lilly Global Supplier Award recognizes Sheffie

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28 February 2010

Sheffield Bio-Science has launched a new brand identity and website to match its industry-leading products, technical expertise and global resources. For more than 65 years, Sheffield has earned its reputation as a successful world-class pharmaceutical supplier that demonstrates excelle

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21 December 2009

Sheffield Bio-Science and Foremost Farms USA have announced a long-term manufacturing agreement that includes a joint investment to expand production of pharmaceutical lactose at Foremost Farms' Rothschild plant. With both companies recognised individually as market leaders, this agreem

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7 October 2009

Visit us at stand 6G48 at CPhI Worldwide 2009 at Fiera de Madrid, Spain, 13-15 October. This year we will be showcasing Kerry flavor modulator technology (fmt™), which provides the perception of sweetness and flavor enhancement to more effectively mask the bitter taste of an API. Read more

20 October 2006

Leading pharmaceutical excipient producers, Kerry Bio-Science Sheffield™ Pharma Ingredients and Foremost Farms USA® announced today that they have formed a strategic marketing alliance which will significantly strengthen their combined market positions. Effective from January 1, 2007, t

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Regional Offices

India Regional Office

Level 2, Raheja Centre Point

294, CST Road

Near Mumbai University, Santacruz (E)

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India

+91 932219 8880
Latin America Regional Office

Ave. Mercedes Benz

460 - Distrito Industrial

Campinas, Sao Paulo

Cep - 13054-750

Other

Brazil

+55 19 3765 5000 +55 19 3765 5108
Sheffield Bio-Science,

Americas Regional Office

158 State Highway 320

Norwich, NY 13815

Other

United States of America

+1 800 833 8308 +1 607 334 5022 www.sheffieldbioscience.com
Asia Pacific Regional Office

460 Alexandra Road

#22-04A/22-05 PSA Building

Singapore 119963

Other

Singapore

+65 6270 3833 +65 6272 2979
Asia Pacific Regional Office

4th Floor, Building No. 92

1122 Qin Zhou Bei Road

Shanghai 200233

Caohejing Hi-Tech Park

Other

China

+86 21 54265333 +86 21 54265350
Europe, Middle East and Africa Regional Office

Veluwezoom 62

1327 AH Almere

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Netherlands

+31 36 523 3100 +31 36 523 3110

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