In Hamburg, Germany, from 30 until 31 May, BMG LABTECH, a microplate reader company, will showcase its newest technology at the European Lab Automation (ELA) 2012. Stop by booth number 120 to see unique and proprietary microplate reader technology that separates BMG LABTECH from the rest. BMG LABTECH features not found on any other instrument include: ultra-fast, full spectrum (220-1000 nm) absorbance analysis for chemical or biological samples; laser-based, light-scattering nephelometery for measuring compound solubility; Atmospheric Control Unit (ACU) for optimising cell-based assay experiments or for inducing disease states such as hypoxia; and direct optic bottom reading for unmatched signal-to-noise ratios in all fluorescent protein assays, such as GFP, YFP and mCherry.
BMG LABTECH will also highlight their microplate readers in several application posters. One poster, presented in conjunction with Pharma Diagnostics, will show how the SoPRano label-free technology is easily executed on a BMG LABTECH spectrometer-based microplate reader. When proteins bind to the SoPRano gold-nano rods, there is a shift in the OD max. This OD max shift is easily monitored with a BMG LABTECH spectrometer-based instrument, which can capture a full spectrum in less than one second per well. This allows protein-protein interactions to be readily monitored with this system.
Another poster, in conjunction with BellBrook Laboratories, describes the generic Transcreener FP assay platform that can be used to measure a diverse set of enzymes in an HTS format, including methyltransferase, acetyltransferase, kinases, ATPases, and GTPases. These robust and highly reproducible assays were performed on the PHERAstar Plus HTS instrument using simultaneous dual emission (SDE) detection. Simultaneous dual emission detection substantially reduces plate read times and it corrects for any signal variations due to differences in well volumes, concentrations, or fluctuations in excitation energy.