AC-0676 is under clinical development by Accutar Biotechnology and currently in Phase I for Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma). According to GlobalData, Phase I drugs for Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma) have a 72% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how AC-0676’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

AC-0676 overview

AC-0676 is under development for the treatment of relapsed/refractory B-cell malignancies (hematological cancers), relapsed/refractory chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), mantle cell lymphoma (MCL), follicular lymphoma (FL), non-GCB diffuse large b-cell lymphoma (DLBCL), marginal zone lymphoma (MZL), or Waldenström macroglobulinemia (WM). The drug candidate targets wild type and c481s mutated froms of tyrosine protein kinase BTK. It is administered through oral route.

It was also under development for the treatment of autoimmune disorders.

Accutar Biotechnology overview

Accutar Biotechnology (Accutar Biotech) is a pharmaceutical drug development company. The company specializes in drug development for breast cancer, prostate cancer, haematology, oncology indications, lung cancer, toxicology, and solid tumors. Its service offerings include clinical trials, drug discovery programs, drug development programs, research and development, and risk management services. The company uses artificial intelligence (AI) platform, data evaluation, deep neural network-based docking platform (orbital), virtual screening, automatic and intelligent lead optimization platform, and deep learning platform for preclinical drug discovery. Accutar Biotech is headquartered in Cranbury, New Jersey, the US.

For a complete picture of AC-0676’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.