AFA-281 is under clinical development by AfaSci and currently in Phase I for Inflammatory Pain. According to GlobalData, Phase I drugs for Inflammatory Pain have an 81% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how AFA-281’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

AFA-281 overview

AFA-281 is under development for the treatment of osteoarthritis, cancer pain, inflammatory pain, neuropathic pain, alcohol use disorder and cocaine use disorder. It is administered through oral and intravenous route. The drug candidate is a dual modulator acts by targeting T-type calcium channels (Cav3) and soluble epoxide hydrolase (sEH).

For a complete picture of AFA-281’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.