Aflibercept Biosimilar is a fusion protein commercialized by Amgen, with a leading Phase III program in Wet (Neovascular / Exudative) Macular Degeneration. According to Globaldata, it is involved in 2 clinical trials, of which 1 was completed, and 1 is ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of Aflibercept Biosimilar’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Aflibercept Biosimilar is expected to reach an annual total of $398 mn by 2038 globally based off GlobalData’s Revenue Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Aflibercept Biosimilar Overview
Aflibercept biosimilar is under development for the treatment of neovascular (wet) age-related macular degeneration (AMD). It is administered through intravitreal (IVT) injection. The drug candidate acts by targeting placenta growth factor (PGF), vascular endothelial growth factor A (VEGF-A)
Amgen Overview
Amgen is a biotechnology company, which discovers, develops, manufactures, and markets innovative human medicines to treat patients suffering from serious diseases. It develops novel medicines in six focused disease areas including cardiovascular diseases, oncology/hematology, inflammation, bone health, neurological disorders and nephrology. The company develops products using advanced human genetics to unravel the difficulties of disease and understand the fundamentals of human biology. Amgen sells products primarily to pharmaceutical wholesale distributors in the US. It also markets certain products directly to consumers through direct-to-consumer channels such as print, television and online media. Amgen is headquartered in Thousand Oaks, California, the US.
The company reported revenues of (US Dollars) US$26,323 million for the fiscal year ended December 2022 (FY2022), an increase of 1.3% over FY2021. The operating profit of the company was US$9,566 million in FY2022, compared to an operating profit of US$7,639 million in FY2021. The net profit of the company was US$6,552 million in FY2022, compared to a net profit of US$5,893 million in FY2021.
For a complete picture of Aflibercept Biosimilar’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.