Antroquinonol is under clinical development by Golden Biotechnology and currently in Phase II for Metastatic Pancreatic Cancer. According to GlobalData, Phase II drugs for Metastatic Pancreatic Cancer have a 31% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Antroquinonol’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Antroquinonol overview
Antroquinonol (Hocena) is under development for the treatment of relapsed acute myeloid leukemia, acute myeloid leukemia, non squamous non small cell lung cancer, metastasis pancreatic cancer, chronic hepatitis B, hepatocellular carcinoma, nonfamilial hypercholesterolemia, mixed hyperlipidemia and Alzheimer's disease. The drug candidate is a small molecule administered orally. It is a new chemical entity (NCE). The drug candidate is a ubiquinone derivate. It is a purified cyclohexenone compound from the extract of Antrodia camphorate. The drug candidate targets farnesyl transferase and down regulates PI3K and mTOR signaling pathways. It was also under development for atopic dermatitis. It was also under development for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with pneumonia.
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Golden Biotechnology overview
Golden Biotechnology (Golden Biotech) is a drug discovery and food supplement manufacturing company. The company develops and commercializes drugs and herbal supplements to prevent and treat several cancer diseases. It discovers new drugs for cardio-metabolic syndromes, autoimmune diseases, neurodegenerative diseases and infectious diseases from the screening platforms. Golden Biotech also offers products under brand names liverty, zsaino, rasle and umooze. It has trial clinical centers for the completion of the Covid-19 in the US, Peru and Argentina. The company markets its products in China, Taiwan, the US, Malaysia and Japan, among others. Golden Biotech is headquartered in New Taipei, Taiwan.
For a complete picture of Antroquinonol’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
