The Apolipoprotein L1 pipeline drugs market research report outlays comprehensive information on the Apolipoprotein L1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Apolipoprotein L1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Genito Urinary System which include the indications Chronic Kidney Disease (Chronic Renal Failure), and Focal Segmental Glomerulosclerosis (FSGS). It also reviews key players involved in Apolipoprotein L1 targeted therapeutics development with respective active and dormant or discontinued products.
The Apolipoprotein L1 pipeline targets constitutes close to seven molecules. Out of which, approximately seven molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase I, Preclinical, and Discovery stages are 1, 2, 3, and 1 respectively.
Apolipoprotein L1 overview
Apolipoprotein L1 is a protein that in humans is encoded by a gene APOL1. This protein is relatively abundant plasma protein available and involved in the formation of most cholesteryl esters in plasma. It promotes efflux of cholesterol from cells, helps in lipid exchange and transport throughout the body. Apolipoprotein L1 also play a role in reverse cholesterol transport from peripheral cells to the liver and in the inflammatory response. Pro-inflammatory cytokines interferon-γ(IFN), tumor necrosis factor-α (TNF-α) and p53 can increase the expression of APOL.
For a complete picture of Apolipoprotein L1’s drug pipeline, buy the report here.
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