AZD-5305 is under clinical development by AstraZeneca and currently in Phase II for Transitional Cell Cancer (Urothelial Cell Cancer). According to GlobalData, Phase II drugs for Transitional Cell Cancer (Urothelial Cell Cancer) have a 25% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how AZD-5305’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
AZD-5305 is under development for the treatment of advanced solid tumors including triple-negative breast cancer, HER2 negative breast cancer, pancreatic cancer, prostate cancer, metastatic prostate cancer, ovarian cancer. fallopian tube cancer, metastatic hormone refractory (castration resistant, androgen-independent) prostate cancer, endometrial cancer, gastric cancer, small-cell lung cancer, esophageal cancer, transitional cell cancer (urothelial cell cancer) and primary peritoneal cancer. It is administered through oral route and acts by targeting Poly (ADP-ribose) polymerase (PARP1).
AstraZeneca is a biopharmaceutical company, which is focused on discovery, production and commercialization of a range of prescription drugs. It develops products related to therapy areas such as respiratory, cardiovascular, renal and metabolic diseases, cancer, autoimmune, infection and neurological diseases. The company’s product portfolio includes biologics, prescription pharmaceuticals and vaccines. AstraZeneca sells its products through wholly- owned local marketing companies, distributors and local representative offices. The company markets its products to primary care and specialty care physicians. The company operates in Europe, the Americas, Asia, Africa and Australasia. AstraZeneca is headquartered in Cambridge, Cambridgeshire, the UK.
For a complete picture of AZD-5305’s drug-specific PTSR and LoA scores, buy the report here.