BMS-986249 is a monoclonal antibody commercialized by Bristol-Myers Squibb, with a leading Phase II program in Metastatic Melanoma. According to Globaldata, it is involved in 1 clinical trial, which is ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of BMS-986249’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for BMS-986249 is expected to reach an annual total of $15 mn by 2038 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
BMS-986249 is under development for the treatment of solid tumors and metastatic melanoma, hepatocellular carcinoma, metastatic castration-resistant prostate cancer and metastatic triple-negative breast cancer. The drug candidate targets CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4). The drug candidate is designed using the Probody platform. It is a probody of ipilimumab. Probodies are fully recombinant, masked antibodies that remain inert in healthy tissue but are activated specifically in the disease microenvironment.
Bristol-Myers Squibb Overview
Bristol-Myers Squibb (BMS) is a specialty biopharmaceutical company that is engaged in discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, cardiovascular, immunology and fibrotic therapeutic projects. The company offers its products across the world to wholesalers, retail pharmacies, hospitals, medical professionals and government entities. BMS provides its products in the US, Europe, and Japan. The company conducts research to focus on the discovery and development of novel medicines that address serious diseases in areas of significant unmet medical need. BMS is headquartered in New York City, New York, the US.
The company reported revenues of (US Dollars) US$46,159 million for the fiscal year ended December 2022 (FY2022), a decrease of 0.5% over FY2021. The operating profit of the company was US$9,665 million in FY2022, compared to an operating profit of US$8,615 million in FY2021. The net profit of the company was US$6,327 million in FY2022, compared to a net profit of US$6,994 million in FY2021.
For a complete picture of BMS-986249’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.