(Carbidopa + levodopa) is under clinical development by Snyder Biomedical and currently in Phase II for Wet (Neovascular / Exudative) Macular Degeneration. According to GlobalData, Phase II drugs for Wet (Neovascular / Exudative) Macular Degeneration have a 57% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how (Carbidopa + levodopa)’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

(Carbidopa + levodopa) overview

The fixed dose combination carbidopa and levodopa is under development for the treatment of neovascular (wet) age-related macular degeneration and dry age-related macular degeneration with geographic atrophy. The therapeutic candidate is administered through oral route in the form of tablet. Levodopa acts by targeting probable G-protein coupled receptor 143 (GPR143) and carbidopa acts by targeting dopa decarboxylase.

For a complete picture of (Carbidopa + levodopa)’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.