Icanbelimod is under clinical development by Suzhou Connect Biopharmaceuticals and currently in Phase II for Ulcerative Colitis. According to GlobalData, Phase II drugs for Ulcerative Colitis have a 44% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Icanbelimod’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Icanbelimod overview
CBP-307 is under development for the treatment of autoimmune diseases including ulcerative colitis, multiple sclerosis, inflammatory bowel disease, graft versus host disease, plaque psoriasis, rheumatoid arthritis. It is administered orally. The drug candidate is a small molecule and it is a second generation S1P1. The drug candidate targets G protein-coupled receptors Sphingosine 1-Phosphate Receptor 1 (S1PR1).
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It was under development for the treatment of crohn's disease.
Suzhou Connect Biopharmaceuticals overview
Suzhou Connect Biopharmaceuticals (Connect Biopharmaceuticals) discovers and develops next-generation immune modulators for the treatment of autoimmune diseases and inflammation. The company’s pipeline Product portfolio includes CBP-307 is an orally-active small molecule used for the treatment of ulcerative colitis (UC) and Crohn’s disease (CD); CBP-201 is an antibody for asthma and atopic dermatitis; and CBP-174 is a small molecule inhibitor for the treatment of chronic skin inflammation. It utilizes T cell modulation technology platform for developing their products. Connect Biopharmaceuticals serves in the therapeutic areas of inflammatory bowel disease, psoriasis, multiple sclerosis and other autoimmune diseases. The company seeks to collaborate with pharmaceutical companies to develop and commercialize their products both inside and outside China. Connect Biopharmaceuticals is headquartered in Taicang, Jiangsu, China.
For a complete picture of Icanbelimod’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
