CCX-872 is under clinical development by Amgen and currently in the Phase I in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect CCX-872’s likelihood of approval (LoA) and phase transition for Metastatic Adenocarcinoma of The Pancreas took place on 21 Oct 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their CCX-872 Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

CCX-872 overview

CCX-872 is under development for the treatment of metastatic adenocarcinoma of the pancreas, glioma, liver fibrosis, non-alcoholic steatohepatitis and focal segmental glomerulosclerosis. The drug candidate is a small molecule and administered orally. CCX-872 is a chemokine receptor-2 (CCR2) antagonist. The drug candidate is based on EnabaLink platform. It was also under development for the treatment of hepatosteatosis (fatty liver disease), atherosclerosis, post myocardial infarction reperfusion injury, vascular endothelial injury and renal disease.

Amgen overview

Amgen is a biotechnology company, which discovers, develops, manufactures, and markets innovative human medicines to treat patients suffering from serious diseases. It develops novel medicines in six focused disease areas including cardiovascular diseases, oncology/hematology, inflammation, bone health, neurological disorders and nephrology. The company develops products using advanced human genetics to unravel the difficulties of disease and understand the fundamentals of human biology. Amgen sells products primarily to pharmaceutical wholesale distributors in the US. It also markets certain products directly to consumers through direct-to-consumer channels such as print, television and online media. Amgen is headquartered in Thousand Oaks, California, the US.

Quick View CCX-872 LOA Data

Report Segments
  • Innovator
Drug Name
  • CCX-872
Administration Pathway
  • Oral
Therapeutic Areas
  • Cardiovascular
  • Gastrointestinal
  • Genito Urinary System And Sex Hormones
  • Oncology
Key Developers
  • Sponsor Company: Amgen
  • Originator: ChemoCentryx
Highest Development Stage
  • Phase I

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.