CGX-1321 is under clinical development by Curegenix and currently in Phase I for Colorectal Cancer. According to GlobalData, Phase I drugs for Colorectal Cancer have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how CGX-1321’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

CGX-1321 overview

CGX-1321 is under development for the treatment of relapsed or refractory solid tumours including adenocarcinomas of the gastrointestinal tract such as colorectal adenocarcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma, gastrointestinal tumor, bile duct carcinoma, hepatocellular carcinoma, oesophagal carcinoma and heart failure with preserved ejection fraction (HFpEF). The drug candidate is administered through the oral route. It is a new chemical entity which acts by targeting porcupine, an acyltransferase that inhibits WNT pathways.

For a complete picture of CGX-1321’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.