Coronavirus Disease 2019 (COVID-19) vaccine is under clinical development by AstraZeneca and currently in Phase I for Middle East Respiratory Syndrome (MERS). According to GlobalData, Phase I drugs for Middle East Respiratory Syndrome (MERS) does not have sufficient historical data to build an indication benchmark PTSR for Phase I. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Coronavirus Disease 2019 (COVID-19) vaccine LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Coronavirus Disease 2019 (COVID-19) vaccine overview

COVID-19 Vaccine (Vaxzevria, AZ Vaccine, Covishield) is a monovalent vaccine composed of a single recombinant, replication-deficient chimpanzee adenovirus (ChAdOx1) vector encoding the S glycoprotein of SARS-CoV-2. It is formulated as injection suspension and solution for intramuscular route of administration. COVID-19 Vaccine is indicated for active immunisation to prevent COVID-19 caused by SARS-CoV-2, in individuals 18 years of age and older. It is also under development for Middle East Respiratory Syndrome (MERS).
AZD-1222 was under development for the prevention of coronavirus disease 2019 (COVID-19). The vaccine candidate comprises of replication-deficient chimpanzee adenovirus vector (ChAdOx1) to deliver Coronavirus spike protein. It is administered through intramuscular and inhalational route.

AstraZeneca overview

AstraZeneca is a biopharmaceutical company, which is focused on discovery, production and commercialization of a range of prescription drugs. It develops products related to therapy areas such as respiratory, cardiovascular, renal and metabolic diseases, cancer, autoimmune, infection and neurological diseases. The company’s product portfolio includes biologics, prescription pharmaceuticals and vaccines. AstraZeneca sells its products through wholly- owned local marketing companies, distributors and local representative offices. The company markets its products to primary care and specialty care physicians. The company operates in Europe, the Americas, Asia, Africa and Australasia. AstraZeneca is headquartered in Cambridge, Cambridgeshire, the UK.

For a complete picture of Coronavirus Disease 2019 (COVID-19) vaccine’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.