Deflexifol is under clinical development by FivePhusion and currently in Phase II for Breast Cancer. According to GlobalData, Phase II drugs for Breast Cancer have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Deflexifol’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Deflexifol overview

Deflexifol is under development for the treatment of solid tumor, breast cancer, gastric cancer, pancreatic cancer, metastatic colorectal cancer, paediatric brain cancer like ependymoma and other rare cancers. It is administered through intravenous route. Deflexifol is an all-in-one injectable reformulation of 5-fluorouracil and leucovorin in which both the drugs linked with cyclodextrin. 5-fluorouracil acts by targeting thymidylate synthase.

For a complete picture of Deflexifol’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.