Deuruxolitinib Phosphate is a small molecule commercialized by Sun Pharmaceutical Industries, with a leading Pre-Registration program in Alopecia Areata. According to Globaldata, it is involved in 1 clinical trial, which was completed. GlobalData uses proprietary data and analytics to provide a complete picture of Deuruxolitinib Phosphate’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.

Smarter leaders trust GlobalData

The revenue for Deuruxolitinib Phosphate is expected to reach an annual total of $257 mn by 2033 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.

Deuruxolitinib Phosphate Overview

Deuruxolitinib phosphate (CTP-543, Deuterated Ruxolitinib) is under development for the treatment of moderate to severe alopecia areata. It is a deuterium-modified analog of ruxolitinib administered orally. It acts by targeting the Janus kinases (JAK1 and JAK2). It is developed based on the DCE (deuterated chemical entity) platform.

Sun Pharmaceutical Industries Overview

Sun Pharmaceutical Industries (Sun Pharma) is a specialty pharmaceutical company that offers an array of pharmaceutical formulations such as branded generics and generic pharmaceuticals. The company’s portfolio includes products for the treatment of psychiatric, neurological, nephrological, gastroenterological, orthopedic and ophthalmologic diseases and disorders, and heart diseases. The company carries out product development, process chemistry, and manufacture of complex formulations, active pharmaceutical ingredients (APIs) and over-the-counter products. It offers drugs in various dosage forms such as tablets, capsules, injectables, inhalers, ointments, creams, and liquids. The company has manufacturing facilities in North America, Latin America, EMEA and Asia Pacific. Sun Pharma is headquartered in Mumbai, Maharashtra, India.
The company reported revenues of (Rupee) INR484,968.5 million for the fiscal year ended March 2024 (FY2024), an increase of 10.5% over FY2023. In FY2024, the company’s operating margin was 20.5%, compared to an operating margin of 20.7% in FY2023. In FY2024, the company recorded a net margin of 19.7%, compared to a net margin of 19.3% in FY2023.

For a complete picture of Deuruxolitinib Phosphate’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.

This content was updated on 10 June 2024

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.

The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.