Dexamethasone XR is under clinical development by Aerie Pharmaceuticals and currently in Phase II for Macular Edema. According to GlobalData, Phase II drugs for Macular Edema have a 67% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Dexamethasone XR’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Dexamethasone XR overview

Dexamethasone is under development for the treatment of wet age related macular degeneration, macular edema from BRVO, macular edema from CRVO and diabetic macular edema. The drug candidate is formulated as an implant and is administered through the intravitreal route. The drug candidate targets glucocorticoid receptors. It is an extended release formulation developed based on particle replication in non-wetting templates (PRINT) technology. This technology engineers highly precise microparticle and nanoparticle systems.

Aerie Pharmaceuticals overview

Aerie Pharmaceuticals (Aerie) is a pharmaceutical company that discovers, develops and commercializes therapies for the treatment of patients with open-angle glaucoma, ocular surface diseases and retinal diseases. The company’s product comprise rhopressa, a once-daily eye drop that is used for the reduction of intraocular pressure in patients with glaucoma or ocular hypertension; and roclatan, a fixed-dose combination of rhopressa and latanoprost. Aerie works in partnership with other pharma companies and universities for drug discovery technologies. The company has presence in the US, UK and Ireland. Aerie is headquartered in Durham, North Carolina, the US.

For a complete picture of Dexamethasone XR’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.