DF-6215 is under clinical development by Dragonfly Therapeutics and currently in Phase I for Head And Neck Cancer. According to GlobalData, Phase I drugs for Head And Neck Cancer have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how DF-6215’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

Smarter leaders trust GlobalData

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

DF-6215 overview

DF-6215 is under development for the treatment of advanced or metastatic solid tumors including melanoma, ovarian cancer, head and neck cancer, HPV-positive advanced malignancies, non-small cell lung cancer and renal cell carcinoma. The therapeutic candidate is a cytokine. It acts by targeting interleukin 2 receptor.

Dragonfly Therapeutics overview

Dragonfly Therapeutics (Dragonfly) is a clinical-stage biotechnology company. It discovers, develops, and commercializes novel immune therapies to treat autoimmune disease, oncology, neuro-inflammation, and others. The company utilizes its proprietary platform, TriNKET, for developing its pipeline products which include DF1001, DF6002, DF9001, and DF6215 drug candidates for the treatment of solid tumors. Dragonfly is also developing various other drug candidates for in collaboartion with companies such as Bristol Myers Squib, Merck, Abbvie, and Gilead. Dragonfly is headquartered in Waltham, Massachusetts, the US.

For a complete picture of DF-6215’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.