Dipraglurant IR is under clinical development by Addex Therapeutics and currently in Phase II for Blepharospasm. According to GlobalData, Phase II drugs for Blepharospasm does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Dipraglurant IR LoA Report. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Dipraglurant IR overview
Dipraglurant IR (ADX-48621) is under development for the treatment of blepharospasm. The drug candidate is administered orally. It is an immediate release formulation. It inhibits the metabotropic glutamate receptor 5 (mGluR5). The drug candidate is based on allosteric modulator discovery technology platform. It was under development for levodopa induced dyskinesia in Parkinson's disease (PD-LID).
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Addex Therapeutics overview
Addex Therapeutics (Addex) is a clinical-stage pharmaceutical company that discovers, develops and commercializes small-molecule pharmaceutical products, including allosteric modulators for neurological disorders. The company develops its proprietary clinical and preclinical-stage drug candidates using its allosteric modulator drug discovery platform. Addex’s lead drug candidate, dipraglurant (mGlu5 negative allosteric modulator or NAM) intended to treat Parkinson’s disease levodopa-induced dyskinesia. It also carries out clinical and preclinical programs for various indications such as dystonia, epilepsy, post-traumatic stress disorder, Schizophrenia, Other Psychosis, addiction, and mild neurocognitive and neurodegenerative disorders. The company has collaboration with Janssen Pharmaceuticals, Indivior PLC, government organizations and other academic researchers. Addex is headquartered in Geneva, Switzerland.
For a complete picture of Dipraglurant IR’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
