The DNA Dependent Protein Kinase Catalytic Subunit pipeline drugs market research report outlays comprehensive information on the DNA Dependent Protein Kinase Catalytic Subunit targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the DNA Dependent Protein Kinase Catalytic Subunit pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, and Undisclosed which include the indications Solid Tumor, Non-Small Cell Lung Cancer, and Unspecified. It also reviews key players involved in DNA Dependent Protein Kinase Catalytic Subunit targeted therapeutics development with respective active and dormant or discontinued products.
The DNA Dependent Protein Kinase Catalytic Subunit pipeline targets constitutes close to 12 molecules. Out of which, approximately 12 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 6, 1, 2, and 2 respectively.
DNA Dependent Protein Kinase Catalytic Subunit overview
DNA-dependent protein kinase catalytic subunit (PRKDC) is a crucial enzyme involved in maintaining genomic integrity by repairing DNA double-strand breaks (DSBs). It plays a pivotal role in the non-homologous end joining (NHEJ) pathway, a major mechanism for repairing DSBs in mammalian cells. DNA-PKcs is a large, 460 kDa protein that belongs to the phosphatidylinositol 3-kinase-related kinase (PIKK) family. Its kinase activity is essential for NHEJ, as it phosphorylates numerous proteins involved in the repair process, including DNA-binding proteins, scaffolding proteins, and DNA ligases.
For a complete picture of DNA Dependent Protein Kinase Catalytic Subunit’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
