Efprezimod alfa is under clinical development by Merck and currently in Phase I for Rheumatoid Arthritis. According to GlobalData, Phase I drugs for Rheumatoid Arthritis have a 71% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Efprezimod alfa’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Efprezimod alfa overview
Efprezimod alfa (MK-7110) is under development for the treatment of rheumatoid arthritis, mucositis, multiple sclerosis. It is administered by intravenous route. CD24Fc is a fusion protein consisting extracellular domain of human CD24 and the Fc of human IgG1. The therapeutic candidate is developed based on technology that targets danger (or damage)-associated molecular patterns (DAMPs) associated pathway. It was also under development for coronavirus disease (COVID-19) infection.
It was under development for the prevention of acute graft versus host disease, dyslipidemias and inflammation in HIV patients.
Merck overview
Merck is a biopharmaceutical company focused on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines and animal health products. It offers prescription products for therapy areas related to cardiovascular, cancer, immune disorders, infectious, respiratory and women’s diseases, and diabetes. The company provides animal health products such as vaccines, poultry products, livestock products and aquaculture products. Merck sells medicines to drug wholesalers, retailers, hospitals, government agencies and managed health care providers; and animal health products to veterinarians, distributors and animal producers. The company and its subsidiaries operate in the Americas, Europe, the Middle East, Africa, Asia Pacific, and Latin America. Merck is known as MSD outside the US and Canada and is headquartered in Kenilworth, New Jersey, the US.
For a complete picture of Efprezimod alfa’s drug-specific PTSR and LoA scores, buy the report here.
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