EQ-101 is under clinical development by Equillium and currently in Phase II for Alopecia Areata. According to GlobalData, Phase II drugs for Alopecia Areata have a 48% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how EQ-101’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

Smarter leaders trust GlobalData

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

EQ-101 overview

EQ-101 is under development for the treatment of T-cell leukemias including large granular leukemia (LGL), refractory cutaneous T-cell lymphoma (CTCL) and alopecia areata. It is a PEGylated 24-amino acid peptide inhibitor of Interleukin-2, Interleukin-9 and Interleukin-15 and administered through intravenous and subcutaneous routes. It is developed based on bioniz technology. The drug candidate was also under development for the treatment of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM-TSP). 

Equillium overview

Equillium is a biotechnology business that specialises in immunobiology to develop drugs for the treatment of autoimmune and inflammatory illnesses.The company’s pipeline product includes EQ001 (itolizumab), a first-in-class monoclonal antibody that targets the novel immune checkpoint receptor CD6 that inhibits pathogenic cellular pathways for effector T cell development. It also develops EQ101 for treatment of cutaneous T cell lymphoma and alopecia areata; and EQ102 to treat various gastrointestinal diseases. Equillium develops its products for immuno-inflammatory diseases across therapeutic areas including transplant science, systemic autoimmunity, gastrointestinal, renal and vascular. Equillium is headquartered in La Jolla, California, the US.

For a complete picture of EQ-101’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.