Gene Therapy to Target PD-L1 for Oncology is under clinical development by Marino Biotechnology and currently in Phase I for Breast Cancer. According to GlobalData, Phase I drugs for Breast Cancer have a 76% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Gene Therapy to Target PD-L1 for Oncology’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Gene Therapy to Target PD-L1 for Oncology overview
Gene therapy is under investigation for the treatment of recurrent glioblastoma multiforme, recurrent or metastatic malignant tumors including pancreatic cancer, kidney cancer, colorectal cancer, breast cancer, lung cancer and lymphoma. It is administered through intravenous infusion. The therapeutic candidate consists of CSR viral vector and is a chimeric switch receptor engineered T cells containing the extracellular domain of PD1 fused to the transmembrane and cytoplasmic domain of the costimulatory molecule CD28. It targets cells expressing programmed cell death 1 ligand 1 (PD L1).
For a complete picture of Gene Therapy to Target PD-L1 for Oncology’s drug-specific PTSR and LoA scores, buy the report here.
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