GFH-009 is under clinical development by SELLAS Life Sciences Group and currently in Phase II for Relapsed Acute Myeloid Leukemia. According to GlobalData, Phase II drugs for Relapsed Acute Myeloid Leukemia have a 20% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how GFH-009’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
GFH-009 is under development for the treatment of refractory and relapsed acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), ewing sarcoma, rhabdomyosarcoma, neuroendocrine prostate cancer and lymphoma, peripheral t-cell lymphomas (PTCL), extranodal marginal zone b-cell lymphoma (mucosa-associated lymphoid tissue or MALT-lymphoma), diffuse large b-cell lymphoma, hodgkin lymphoma (b-cell hodgkin lymphoma). The drug candidate is administered by intravenous route. It acts by targeting cyclin-dependent kinase 9 (CDK9).
SELLAS Life Sciences Group overview
SELLAS Life Sciences Group (SELLAS), formerly Galena Biopharma, develops novel cancer immunotherapeutics for multiple cancer treatments. Its pipeline product candidates include galinpepimut-S (GPS), a wilms tumor1 (WT1) protein-targeting synthetic heteroclitic epitope immunotherapeutic antigen used for the treatment of acute myeloid leukemia, ovarian cancer, malignant pleural mesothelioma, multiple myeloma and solid tumors; and Nelipepimut-S, a vaccine derived from the human epidermal growth factor 2 or HER2 protein for the prevention of breast cancer and gastric carcinomas. The company collaborates with Memorial Sloan Kettering Cancer Center (MSKCC), National Cancer Institute (NCI) and The University of Texas M.D. Anderson Cancer Center (MDACC) for conducting clinical trials targeting multiple cancer indications. SELLAS is headquartered in New York City, New York, the US.
For a complete picture of GFH-009’s drug-specific PTSR and LoA scores, buy the report here.