The Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta pipeline drugs market research report outlays comprehensive information on the Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Genito Urinary System, and Gastrointestinal which include the indications Melanoma, Glioblastoma Multiforme (GBM), Inflammation, Acute Renal Failure (ARF) (Acute Kidney Injury), and Inflammatory Bowel Disease. It also reviews key players involved in Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta targeted therapeutics development with respective active and dormant or discontinued products.
The Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta pipeline targets constitutes close to nine molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, and Preclinical stages are 1, and 5 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 2, and 1 molecule.
Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta overview
Inhibitor of nuclear factor kappa-B kinase subunit beta is a protein encoded by the IKBKB gene. It plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. It acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. Free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis.
For a complete picture of Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta’s drug pipeline, buy the report here.
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