The Pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Alkoxysilyl compounds.

However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilising and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

110 innovations will shape the pharmaceutical industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 756,000 patents, there are 110 innovation areas that will shape the future of the industry.

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Adeno-associated virus vectors, alcohol dehydrogenase compositions, and alkoxysilyl compounds are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are anti-influenza antibody compositions and anti-interleukin-1, which are now well established in the industry.

Innovation S-curve for the pharmaceutical industry

Alkoxysilyl compounds is a key innovation area in pharmaceutical

Alkoxysilyl compounds are siloxane-based nanomaterials used in molecular assembly, nano-building block linkage, and in oligosiloxane compound synthesis. They are used in various applications such as pharmaceuticals, herbicides, and insecticides.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 40+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of alkoxysilyl compounds.

Key players in alkoxysilyl compounds – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of different applications identified for each relevant patent and broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of different countries each relevant patent is registered in and reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to alkoxysilyl compounds

Company Total patents (2010 - 2021) Premium intelligence on the world's largest companies
Scipharm 49 Unlock company profile
Shin-Etsu Chemical 46 Unlock company profile
LG 43 Unlock company profile
Uni-President China Holdings 40 Unlock company profile
Henkel 35 Unlock company profile
KCC 33 Unlock company profile
DR. Alexander Wacker Familiengesellschaft MIT Beschraenkter Haftung 33 Unlock company profile
Ocuphire Pharma 30 Unlock company profile
Incyte 28 Unlock company profile
Shikoku Chemicals 28 Unlock company profile
United Therapeutics 25 Unlock company profile
RAG-Stiftung 25 Unlock company profile
BASF 24 Unlock company profile
Eisai 22 Unlock company profile
Zhejiang Ausun Pharmaceutical 19 Unlock company profile
Dow 19 Unlock company profile
Lanxess 19 Unlock company profile
Sekisui Chemical 18 Unlock company profile
3M 15 Unlock company profile
Gedeon Richter 14 Unlock company profile
E. Merck 13 Unlock company profile
Silecs 11 Unlock company profile
Goodyear Tire & Rubber 10 Unlock company profile
Grupo Kuo SAB de CV 10 Unlock company profile
Chirogate International 10 Unlock company profile
Sigilon Therapeutics 10 Unlock company profile
Fabbrica Italiana Sintetici 10 Unlock company profile
Arbutus Biopharma 9 Unlock company profile
Jingzhou Jianghan Fine Chemical 9 Unlock company profile
Nissan Chemical 9 Unlock company profile
Arkema 8 Unlock company profile
Yonsung Fine Chemicals 8 Unlock company profile
CEKO 8 Unlock company profile
HEC Pharm Group 8 Unlock company profile
Albemarle 8 Unlock company profile
Lunan Pharmaceutical Group 6 Unlock company profile
Ivoclar Vivadent 6 Unlock company profile
Agilent Technologies 6 Unlock company profile
Huntsman 6 Unlock company profile
Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung 6 Unlock company profile
Atotech 5 Unlock company profile
Shofu 5 Unlock company profile
Wanhua Chemical Group 5 Unlock company profile
CVC Capital Partners SICAV-FIS 5 Unlock company profile
Seino Holdings 5 Unlock company profile

Source: GlobalData Patent Analytics

Scipharm is the leading patent filer for Alkoxysilyl compounds. Trepulmix (Treprostinil), which is one of the company’s marketed drugs, is manufactured by using this compound. Shin-Etsu Chemical and LG are the other key patent filers for Alkoxysilyl compounds.

In terms of application diversity, Sigilon Therapeutics is the top company, followed by Albemarle and Seino. By means of geographic reach, Ocuphire Pharma held the top position. Scipharm and Lanxess stood in the second and third positions, respectively. To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.