The Integrin Beta 3 pipeline drugs market research report outlays comprehensive information on the Integrin Beta 3 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Integrin Beta 3 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Ophthalmology, Cardiovascular, and Dermatology which include the indications Breast Cancer, Glioblastoma Multiforme (GBM), Wet (Neovascular / Exudative) Macular Degeneration, Persistent Corneal Epithelial Defects, Thrombosis, Coronary Artery Disease (CAD) (Ischemic Heart Disease), and Wounds. It also reviews key players involved in Integrin Beta 3 targeted therapeutics development with respective active and dormant or discontinued products.
The Integrin Beta 3 pipeline targets constitutes close to 31 molecules. Out of which, approximately 24 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, and Preclinical stages are 1, 1, 3, 4, 1, and 14 respectively. Similarly, the universities portfolio in Preclinical comprises 7 molecule.
Integrin Beta 3 overview
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. Integrin beta 3 is found along with the alpha IIb chain in platelets. It is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Activation of integrin alpha-IIb/beta-3 leads to platelet interaction through binding of soluble fibrinogen. This leads to rapid platelet aggregation which physically plugs ruptured endothelial surface.
For a complete picture of Integrin Beta 3’s drug pipeline, buy the report here.
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