The Interleukin 18 pipeline drugs market research report outlays comprehensive information on the Interleukin 18 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Interleukin 18 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Gastrointestinal, and Infectious Disease which include the indications Glioblastoma Multiforme (GBM), Kidney Cancer (Renal Cell Cancer), Inflammation, Pulmonary Sarcoidosis, Ulcerative Colitis, Crohn’s Disease (Regional Enteritis), Coronavirus Disease 2019 (COVID-19), and Coronavirus Disease 2019 (COVID-19) Pneumonia. It also reviews key players involved in Interleukin 18 targeted therapeutics development with respective active and dormant or discontinued products.
The Interleukin 18 pipeline targets constitutes close to 11 molecules. Out of which, approximately ten molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 3, 1, 1, 2, and 2 respectively. Similarly, the universities portfolio in Phase I comprises 1 molecule.
Interleukin 18 overview
Interleukin 18 (IL18) is a proinflammatory cytokine of the IL-1 family that is found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. It is involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, triggering synthesis of inflammatory mediators.
For a complete picture of Interleukin 18’s drug pipeline, buy the report here.
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