KOS-1803 is under clinical development by Bristol-Myers Squibb and currently in the Phase I in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.
According to GlobalData, the latest event to affect KOS-1803’s likelihood of approval (LoA) and phase transition for Solid Tumor took place on 27 Jun 2022, which decreased the likelihood that the drug progresses to the next phase in its clinical pathway.
GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their KOS-1803 Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.
KOS-1803 (Iso-Fludelone) is under development for the treatment of advanced solid tumors. The drug candidate is administered through intravenous route. Iso-Fludelone is a third-generation epothilone B analog. It binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization. The drug candidate was under development for the treatment of breast, lung, prostate and colorectal cancers, ovarian cancer and neuroblastoma.
Bristol-Myers Squibb overview
Bristol-Myers Squibb (BMS) is a specialty biopharmaceutical company that is engaged in discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, cardiovascular, immunology and fibrotic therapeutic projects. The company offers its products across the world to wholesalers, retail pharmacies, hospitals, medical professionals and government entities. BMS provides its products in the US, Europe, and Japan. The company conducts research to focus on the discovery and development of novel medicines that address serious diseases in areas of significant unmet medical need. BMS is headquartered in New York City, New York, the US.
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