Luxeptinib is under clinical development by CrystalGenomics and currently in the Phase I in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Luxeptinib’s likelihood of approval (LoA) and phase transition for Refractory Acute Myeloid Leukemia took place on 24 Oct 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

In addition, the same event on 24 Oct 2022 increased Luxeptinib’s LoA and PTSR for Relapsed Acute Myeloid Leukemia.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Luxeptinib Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Luxeptinib overview

CG-806 is under development for the treatment of relasped/refractory acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), r/r chronic lymphocytic leukemia, small lymphocytic lymphoma, Waldenstrom Macroglobulinemia, mantle cell lymphoma, follicular lymphoma and diffuse large B-cell lymphoma. It is a pan-FLT3/BTK inhibitor and act by targeting FLT3 (FMS-like tyrosine kinase 3) and brew button tyrosine kinase (bruton tyrosine kinase, BTK) along with CSF1R, PDGFRα, TRK, AURK, others. It is administered through the oral route. The drug candidate is developed based on a combination of soluble protein solution (SPS), structural chemo proteomics (SCP), structural-based drug factory (SDF) platforms.

CrystalGenomics overview

CrystalGenomics is a biopharmaceutical company that discovers and develops structural chemoproteiomics-based drugs. The company’s pipeline products include CG-650 used for the treatment of acute chronic pain; CG-651, targeting neuropathic pain; CG-598 against inflammatory bowel disease; CG-549 used for the treatment of infectious diseases; CG-745 investigating for the traetment of pancreatic cancer, myelodysplastic syndrome and acute myeloid leukemia; CG-806, against blood cancer and CG-750 for treating fibrosis. CrystalGenomics uses its proprietary technologies to determine the structure of proteins, generate lead compounds; and optimize novel leads to drug candidate compounds. The company also provides soluble, active and homogeneous forms of disease related proteins. CrystalGenomics is headquartered in Seongnam, South Korea.

Quick View Luxeptinib LOA Data

Report Segments
  • Innovator
Drug Name
  • Luxeptinib
Administration Pathway
  • Oral
Therapeutic Areas
  • Oncology
Key Developers
Highest Development Stage
  • Phase I

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.