Magrolimab is under clinical development by Gilead Sciences and currently in Phase I for Fallopian Tube Cancer. According to GlobalData, Phase I drugs for Fallopian Tube Cancer have an 84% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Magrolimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Magrolimab overview

Magrolimab is under development for the treatment of solid tumor, relapsed/refractory multiple myeloma, oral cavity cancer, oropharyngeal cancer, hypopharyngeal cancer, laryngeal cancer, pancreatic ductal adenocarcinoma, urethral cancer, ureter cancer, breast cancer, colorectal cancer, epithelial ovarian cancer, fallopian tube cancer, peritoneal cancer, head and neck cancer, ovarian, indolent lymphoma, metastatic transitional (urothelial) tract cancer, bladder cancer, and atherosclerosis. It is a humanized IgG4 subclass monoclonal antibody. The drug candidate is administered through intravenous route. It acts by targeting CD47.

It was also under development for metastatic small cell lung cancer and metastatic non-small cell lung cancer, metastatic colorectal cancer, recurrent head and neck squamous cell carcinoma, triple negative breast cancer, cutaneous T-cell lymphoma, Hodgkin lymphoma., previously untreated, relapsed or refractory acute myelocytic leukemia, NHL, myelodysplastic syndrome, relapsed and refractory B-cell non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, ependymoma, marginal zone or follicular lymphoma.

Gilead Sciences overview

Gilead Sciences (Gilead) is a research-based biopharmaceutical company. It carries out the discovery, development and commercialization of medicines for the treatment of cardiovascular, hematological and respiratory diseases, inflammation, liver diseases such as hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, cancer, and human immunodeficiency virus (HIV) infection. It markets its products through commercial teams, third-party distributors and corporate partners. Gilead’s commercial teams promote its products through direct field contact with physicians, hospitals, clinics and other healthcare providers. The company sells its products through subsidiaries and distributors in Europe, the Americas, Asia-Pacific, the Middle East, and Africa. Gilead is headquartered in Foster City, California, the US.

For a complete picture of Magrolimab’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.