Mecbotamab vedotin is under clinical development by BioAtla and currently in the Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Mecbotamab vedotin’s likelihood of approval (LoA) and phase transition for Pancreatic Cancer took place on 28 Sep 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway and increased the likelihood of final approval for this indication.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Mecbotamab vedotin Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Mecbotamab vedotin overview

BA-3011 is under development for the treatment of solid tumors include non-small cell lung cancer (NSCLC), oral cancer, castration-resistant prostate cancer (CRPC), bladder cancer, breast cancer, fallopian tube cancer and peritoneal cancer, colorectal cancer, oral cancer, cervical cancer, ovarian cancer, head and neck cancer, liver cancer, lung cancer, melanoma, stomach cancer, pancreatic cancer, soft tissue sarcoma, osteosarcoma, bone sarcoma, Ewing sarcoma and endometrial cancer, chondrosarcoma, adenoid cystic carcinoma (ACC), renal cell carcinoma, mesothelioma of the pleura, leiomyosarcoma, synovial sarcoma, liposarcoma. The drug candidate acts by targeting AXL receptor tyrosine kinase. The drug candidate is developed based on  conditionally active biologics (CAB) platforms.

BioAtla overview

BioAtla is a clinical-stage biopharmaceutical company that focused on on developing antibody-based therapeutics for the treatment of solid tumor cancer. The company product candidate includes BA3011, BA3021 and BA3071, BA3182, BA3142, BA3311, BA336 and BA3151. BioAtla lead product candidate, BA3011, is a conditionally active biologics (CAB) antibody-drug conjugates (ADC) that targets AXL, which is protein kinase receptor. Its BA3021 is developing a CAB antibody drug conjugate directed against receptor tyrosine kinase such as orphan receptor 2 (ROR2), BA3071 is therapeutic for multiple solid tumor indications, including renal cell carcinoma, NSCLC, small cell lung cancer, hepatocellular carcinoma, melanoma, bladder cancer, gastric cancer and cervical cancer. The company offers laboratories in the US and China. BioAtla is headquartered in San Diego, California, the US.

Quick View Mecbotamab vedotin LOA Data

Report Segments
  • Innovator
Drug Name
  • Mecbotamab vedotin
Administration Pathway
Therapeutic Areas
  • Oncology
Key Developers
Highest Development Stage
  • Phase II

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.