Merestinib is under clinical development by Eli Lilly and Co and currently in the Phase I and Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.
According to GlobalData, the latest event to affect Merestinib’s likelihood of approval (LoA) and phase transition for Metastatic Biliary Tract Cancer took place on 05 Sep 2022, which decreased the likelihood that the drug progresses to the next phase in its clinical pathway.
GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Merestinib Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.
Merestinib (LY-2801653) is under development for the treatment of solid tumors including metastatic biliary tract adenocarcinoma, gallbladder cancer, non-small cell lung cancer, metastatic colorectal cancer, adenocarcinoma of the colon or rectum, cholangiocarcinoma, and non-small cell lung cancer, heamatological cancers including non-Hodgkin lymphoma, mantle cell lymphoma, relapsed and refractory acute myeloid leukemia. It is administered orally. The drug candidate is a new chemical entity (NCE). It acts by targeting c-Met, other receptor tyrosine oncokinases including MST1R, FLT3, AXL, MERTK, TEK, ROS1, and DDR1/2 and the serine/threonine kinases MKNK1/2. It was also under development for uveal melanoma with liver with metastasis, bone metastasis associated with breast cancer, gastric cancer, adenocarcinoma of gastroesophageal junction and head and neck squamous cell carcinoma.
Eli Lilly and Co overview
Eli Lilly and Co (Lilly) is a healthcare company that is engaged in the discovery, development, and marketing of human healthcare products. The company offers medicines for cardiovascular conditions, diabetes, endocrinology, cancer, neurological problems, immune disorders, men’s health and musculoskeletal problems. The company distributes its pharmaceutical health products through independent wholesale distributors. Lilly conducts research and development activities to discover and deliver innovative medicines. It also promotes products through sales representatives and marketing agreements with other pharmaceutical companies. The company also offers its products in North America, South America, Europe, South Asia, the Middle East, Africa and North Asia-Pacific. Lilly is headquartered in Indianapolis, Indiana, the US.
Quick View Merestinib LOA Data
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