MVXONCO-1 is under clinical development by MaxiVAX and currently in the Phase I and Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect MVXONCO-1’s likelihood of approval (LoA) and phase transition for Chordoma took place on 27 Dec 2022, which increased the likelihood that the drug progresses to the next phase in its clinical pathway.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their MVXONCO-1 Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

MVXONCO-1 overview

MVXONCO-1 is under development for the treatment of lung carcinoma (either small cell or non-small cell), colon, breast, pancreas (exocrine or endocrine), stomach, oesophagus, head and neck squamous cell carcinoma, thyroid, kidney, bladder, prostate, ovary, uterus (cervix or corpus), sarcoma of soft tissue, bone, uterus, melanoma, chordoma and primary brain tumor. The drug candidate is a personalized vaccine administered subcutaneously as injections and capsules implantations. The drug candidate is a combination of two components, MVX-1-loaded microcapsules and irradiated autologous tumor cells.

MaxiVAX overview

MaxiVAX is a clinical stage biotechnology company that develops active immunotherapy with encapsulated cells for the treatment of cancer. Its lead product candidate includes MVX-ONCO-1, an immuno-oncology therapeutic vaccination that activates the patient’s own natural immune response mechanism through an innovative and proprietary technology in order to eliminate the deadly cancer cells. Its MVX-ONCO-1 consists of a small device and is placed underneath the skin. MaxiVAX’s product is composed of irradiated tumour cells of the patient and an immune-boosting agent, released from an encapsulated, cells being protected by the capsule from elimination by the patient’s immune response, thus produce locally the substance of interest locally for several weeks, genetically modified cell line. The company also conducts Phase 2 clinical study for the treatment of head and neck cancer, and several solid tumors. MaxiVAX is headquartered in Geneva, Switzerland.

Quick View MVXONCO-1 LOA Data

Report Segments
  • Innovator
Drug Name
Administration Pathway
  • Subcutaneous
Therapeutic Areas
  • Oncology
Key Developers
Highest Development Stage
  • Phase II

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.