ND-0612 is under clinical development by Mitsubishi Tanabe Pharma and currently in the Phase III in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.
According to GlobalData, the latest event to affect ND-0612’s likelihood of approval (LoA) and phase transition for Parkinson’s Disease took place on 02 Feb 2021, which decreased the likelihood that the drug progresses to the next phase in its clinical pathway and decreased the likelihood of final approval for this indication.
GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their ND-0612 Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.
ND-0612 overview
ND-0612 is under development as an adjunct to oral levodopa for the treatment of moderate to severe Parkinson's disease. The drug candidate is a liquid fixed dose combination of levodopa and carbidopa administered through a patch-pump or belt pump to deliver controlled dose continuously as subcutaneous infusion. It is formulated as both high dose (ND-0612H) and low dose (ND-0612L) liquid formulation. The drug candidate acts by targeting dopa decarboxylase and dopaminergic receptors (D1, D2, D3, D4 and D5).
Mitsubishi Tanabe Pharma overview
Mitsubishi Tanabe Pharma (Mitsubishi Tanabe), a subsidiary of Mitsubishi Chemical Holdings Corp, identifies, develops, manufactures, procures, and commercializes ethical drugs and over the counter (OTC) pharmaceutical products. The company develops ethical drugs for autoimmune disease, diabetes, kidney diseases, central nervous system (CNS) disorders, and others. It also develops vaccines for preventing various infectious diseases. Mitsubishi Tanabe also offers major products for skin conditions and digestive medicines. The company markets its products to wholesalers, hospitals, clinics, and drugstores. It has subsidiaries in Asia, Europe, and North America. Mitsubishi Tanabe is headquartered in Osaka, Japan.
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