NEX-0033744 is under clinical development by Nxera Pharma and currently in Phase I for Crohn’s Disease (Regional Enteritis). According to GlobalData, Phase I drugs for Crohn’s Disease (Regional Enteritis) have an 81% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how NEX-0033744’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

NEX-0033744 overview

Small molecule is under development for the treatment of inflammatory bowel disease including crohn's disease. The drug candidate acts by targeting prostanoid EP4 receptor. It is administered through oral route.

Nxera Pharma overview

Nxera Pharma, formerly Sosei Group Corp, is a biopharmaceutical company that develops drugs by using a proprietary G protein-coupled receptor (GPCR) targeted StaR technology and structure-based drug discovery (SBDD) platform. Its medical products include ultibro, seebri, enerzair, breezhaler, pivlaz and oravi. The company’s in-house pipeline programs include H4 antagonist, EP4 antagonist, SARS-CoV-2 MPro, GPR52 agonist and PAR2 mAb. Nxera Pharma partnered pipeline program comprises CCR6 antagonist, muscarinic M4 agonist, MC4 antagonist, muscarinic M1 agonist, dual muscarinic M1 and M4 agonists, GPR35 agonist, CXCR4 mAb, PAR2 peptide, targeted GPCR degradation, ion channels, OX2 agonist and mGlu5 NAM, among others. The company operates in Japan, South Korea, Ireland and the UK. Nxera Pharma is headquartered in Chiyoda-ku, Tokyo, Japan.

For a complete picture of NEX-0033744’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.