NUC-7738 is under clinical development by NuCana and currently in Phase II for Renal Cell Carcinoma. According to GlobalData, Phase II drugs for Renal Cell Carcinoma have a 29% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how NUC-7738’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
NUC-7738 overview
NUC-7738 is under development for the treatment of solid tumors including metastatic cutaneous melanoma, metastatic lung adenocarcinoma, metastatic clival chordoma, B-cell non-Hodgkin lymphomas (NHL), Hodgkin's lymphoma, T-cell lymphomas, lymphoma and kidney cancer. It is a protide transformation of cordycepin. It acts by targeting adenosine monophosphate activated protein kinase (AMPK). The drug candidate is developed based on ProTide technology.
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NuCana overview
NuCana is a clinical-stage biopharmaceutical company that develops novel and transformational medicines for the treatment of cancer. The company pipeline products include NUTIDE-302, NUTIDE-323, NUTIDE-303 and NUTIDE-701 under the clinical studies NUC-3373 and NUC-7738. The company’s product candidates treat colorectal cancer, solid tumor and lung cancer, among others. NuCana develops products based on the ProTide technology platform, which focuses on developing new-generation, anti-cancer agents. The company operates in UK and the US. NuCana is headquartered in Edinburgh, Scotland, the UK
For a complete picture of NUC-7738’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
